Associations Between Fatty Acid Levels in Human Blood and Trigeminovascular Tissues
Lipids, EarlyView.ABSTRACT Omega‐3 and omega‐6 polyunsaturated fatty acids (PUFAs) are precursors to oxylipins that modulate pain and inflammation. We previously demonstrated that (1) a dietary intervention increasing omega‐3 and reducing omega‐6 PUFAs alters the concentration of these oxylipin precursors in blood, and (2) these changes are associated with reduced ...
Daisy Zamora +8 more
wiley +1 more source
Neuropeptide Co-Release with Gaba May Explain Functional Non-Monotonic Uncertainty Responses in Dopamine Neurons [PDF]
, 2007 Co-release of the inhibitory neurotransmitter GABA and the neuropeptide substance-P (SP) from single axons is a conspicuous feature of the basal ganglia, yet its computational role, if any, has not been resolved.
Bullock, Daniel, Tan, Can Ozan
core +1 more source
Cocaine- and Amphetamine-Regulated Transcript (CART) Is Colocalized with the Orexigenic Neuropeptide Y and Agouti-Related Protein and Absent from the Anorexigenic α-Melanocyte-Stimulating Hormone Neurons in the Infundibular Nucleus of the Human Hypothalamus [PDF]
, 2007 Judit Menyhért +5 more
openalex +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley +1 more source
Diet transition to a high-fat diet for 3 weeks reduces brain omega-3-fatty acid levels, alters BDNF signaling and induces anxiety & depression-like behavior in adult rats [PDF]
, 2012 Background: The consumption of diets high in calories and low in nutrient value is becoming increasingly common in modern society, which can lead to metabolic disorders like diabetes and obesity, and potentially to psychiatric disorders.
Fernando Gomez-Pinilla +2 more
core +1 more source
Movement Disorders, EarlyView.Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag +14 more
wiley +1 more source
Movement Disorders, EarlyView.The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger +1 more
wiley +1 more source
In silico analysis of crustacean hyperglycemic hormone family G protein-coupled receptor candidates
Frontiers in EndocrinologyEcdysteroid molting hormone synthesis is directed by a pair of molting glands or Y-organs (YOs), and this synthesis is inhibited by molt-inhibiting hormone (MIH).
Mihika T. Kozma +8 more
doaj +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Aims To explore the boundary of clinical use of sacral nerve stimulation (SNS) in neurogenic lower urinary tract dysfunction (NLUTD), identifying barriers to approval and early‐impact research questions. Methods This review is derived from a proposal discussion at the International Consultation on Incontinence‐Research Society in Bristol in ...
Marcus J. Drake +6 more
wiley +1 more source
From gonadotropin-inhibitory hormone to SIFamides: Are echinoderm SALMFamides the "missing link" in a bilaterian family of neuropeptides that regulate reproductive processes? [PDF]
, 2013 Bentley +46 more
core +1 more source