Results 121 to 130 of about 88,878 (295)
Modulation of immunity and hypersensitivity by sensory neuropeptides. [PDF]
D G Payan, J D Levine, E J Goetzl
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Contribution of perineuronal nets to hyperexcitability in pilocarpine‐induced status epilepticus
Abstract Objective Changes in extracellular matrix (ECM) and highly condensed ECM structures called perineuronal nets (PNNs) have been reported in human patients with epilepsy as well as some animal models of epilepsy. We studied potential ECM changes in a mouse model of pilocarpine‐induced status epilepticus (PISE) and their potential contributions to
AnnaLin M. Woo+3 more
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Modulation of lymphocyte function by sensory neuropeptides [PDF]
DG Payan, EJ Goetzl
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Osteochondrosis in horses: An overview of genetic and other factors
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez+2 more
wiley +1 more source
Estrogen synthesized in the central nervous system enhances MC4R expression and reduces food intake
Estrogen is regulated by the rate‐limiting enzyme aromatase. This study examines how neuroestrogens, estrogen produced in the brain, regulate appetite through the hypothalamus. Using ovariectomized, aromatase knockout, and brain‐specific aromatase‐restored mice, the study found that neuroestrogens suppress appetite by influencing genes like Mc4r.
Takanori Hayashi+8 more
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Emerging roles for integrated stress response signaling in homeostasis
Integrated stress response (ISR), an evolutionarily conserved eukaryotic stress‐adaptive program in eukaryotes, has also been implicated in homeostatic functions. This review covers a broad body of literature and presents several homeostatic functions of ISR in the absence of stress: (a) developmental processes (morphogenesis, differentiation, aging), (
Shyama Nandakumar+2 more
wiley +1 more source
Neuropeptide proctolin in postural motoneurons of the crayfish [PDF]
CA Bishop, JJ Wine, Michael O’Shea
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