Results 201 to 210 of about 204,831 (332)

TRPM3 activation causes CGRP release in trigeminal neurons: Implications for migraine mechanisms

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Background The transient receptor potential melastatin 3 (TRPM3) ion channel has been implicated in sensory modulation and pain transmission and may contribute to migraine pathophysiology through calcitonin gene‐related peptide (CGRP) release in the trigeminovascular system. This study aimed to investigate TRPM3 activation and its role in CGRP
Philip V. Reducha, Lukas K. S. Nielsen, Mette N. Jensen, Jacob C. A. Edvinsson, Spyridoula Kazantzi, Sofia L. Wæver, Tanja Lylloff, Connar S. J. Westgate, Lars Edvinsson, Kristian A. Haanes   +9 more
wiley   +1 more source

Molecular mechanisms and therapeutic implications of the sympathetic nervous system in bone-related disorders: a brain-bone axis perspective. [PDF]

Bone Res
Liu M, Liu Y, Yu J, Gong J, Zhao C, Liu Z.   +5 more
europepmc   +1 more source

The differences in local translatome across distinct neuron types is mediated by both baseline cellular differences and post-transcriptional mechanisms [PDF]

, 2018
Aryal, Shivani, Dougherty, Joseph D, Lagunas, Tomas, Lake, Allison M, Ouwenga, Rebecca   +4 more
core   +1 more source

Real‐world effectiveness and safety of galcanezumab for the treatment of migraine: A systematic review and meta‐analysis

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to summarize and pool real‐world evidence on the clinical effectiveness and safety of galcanezumab. Background Migraine is a disabling primary headache disorder. Several drugs that target calcitonin gene‐related peptide, such as galcanezumab, have recently been developed.
Jaime Fernández‐Bravo‐Rodrigo, Carlos Pascual‐Morena, Alicia Saz‐Lara, Irene Martínez‐García, Carla Geovanna Lever‐Megina, Silvana Patiño‐Cardona, Amparo Flor‐García, Iván Cavero‐Redondo   +7 more
wiley   +1 more source

Toward high-efficiency, low-resource, and explainable neuropeptide prediction with MSKDNP. [PDF]

Brief Bioinform
Xie P, Guan J, Zhao Z, Liu Y, Cheng Z, He X, Liu X, Tang Y, Sun Z, Lee TY, Yao L, Chiang YC.   +11 more
europepmc   +1 more source

Inhibitory effects of MK801 on activation of MAP kinase In adult rat hippocampus after Intracerebroventricular injections of glutamate, somatostatin and neuropeptide Y

, 1998
Kouji Fukushima, Tadashi Umekage, Vasutomi Kuroki, Yasunari Kanda, Eisuke Nishio, Yuji Saito, Yasuhiro Watanabe   +6 more
openalex   +1 more source

A retrospective audit of the real‐world safety and effectiveness profile of eptinezumab for treatment‐resistant chronic migraine in Australia

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To describe the real‐world safety, tolerability, and effectiveness of eptinezumab for chronic migraine prevention in Australia. Background Eptinezumab is a relatively new medication for treatment‐resistant chronic migraine prevention.
Lakshini Gunasekera, Shuli Cheng, Emma Foster, Shobi Sivathamboo, Terence O'Brien, Helmut Butzkueven, Jayashri Kulkarni, Elspeth Hutton   +7 more
wiley   +1 more source

Pituitary adenylate cyclase-activating polypeptide modulates circadian feeding and emotional behavior in mice independent of stress-induced hyperphagia. [PDF]

Vet World
Nguyen HTT, Mai TN, Vu TTT, Nguyen TT.
europepmc   +1 more source

Modulation of locomotion and reproduction by FLP neuropeptides in the nematode Caenorhabditis elegans

, 2015
Chris Li
openalex   +1 more source

Amplifying and ameliorating light avoidance in mice with photoreceptor targeting and calcitonin gene‐related peptide sensitization

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The aim of this study was to determine the photoreceptor basis of light avoidance in mice and assess the effect of CGRP sensitization on this behavior. Background Prior studies have suggested that photophobia is mediated by a subset of retinal ganglion cells (RGCs) that contain melanopsin, making them intrinsically photosensitive ...
Eric A. Kaiser, Audrey Cavanah, Geoffrey K. Aguirre, Frances E. Jensen   +3 more
wiley   +1 more source