Results 201 to 210 of about 221,321 (383)

Galcanezumab reduces trigeminal nociception and is effective in preclinical models of migraine and trigeminal autonomic cephalalgias

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This study was undertaken to assess the therapeutic efficacy of galcanezumab in preclinical models of migraine and cluster headache and to determine potential shared trigeminovascular mechanisms of action. Galcanezumab is a humanized monoclonal antibody that binds to the neuropeptide calcitonin gene‐related peptide ...
Marta Vila‐Pueyo, Peter J. Goadsby, Kirk W. Johnson, Philip R. Holland   +3 more
wiley   +1 more source

From gonadotropin-inhibitory hormone to SIFamides: Are echinoderm SALMFamides the "missing link" in a bilaterian family of neuropeptides that regulate reproductive processes? [PDF]

, 2013
Bentley, Bonini, Broeck, Dockray, Díaz-Miranda, Elphick, Elphick, Elphick, Elphick, Elphick, Elphick, Elphick, Elshourbagy, Gouarderes, Hartenstein, Hewes, Hinuma, Janssen, Jekely, Jorgensen, Krishnan, Li, Liu, Maurice R. Elphick, Melarange, Melarange, Mirabeau, Mita, Mita, Mollereau, Newman, Newman, Perry, Putnam, Rowe, Satake, Terhzaz, Tsutsui, Ubuka, Ubuka, Van Kesteren, Veenstra, Veenstra, Vilim, Yang, Yasuda, Zhang   +46 more
core   +1 more source

Independent Regulation of Neuropeptide mRNA Level and Poly(A) Tail Length

, 1989
David Carter, David Murphy
openalex   +1 more source

Changes in brainstem habituation during onabotulinumtoxinA treatment in chronic migraine: A prospective case–control study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Chronic migraine is a debilitating neurological disorder characterized by central sensitization and impaired brainstem habituation. OnabotulinumtoxinA is an established prophylactic treatment for chronic migraine, yet its effects on central trigeminal sensory processing remain incompletely understood.
Gerlinde Freimark, Sebastian Strauss, Lucas H. Overeem, Mira P. Fitzek, Kristin S. Lange, Carolin L. Höhne, Uwe Reuter, Robert Fleischmann, Bianca Raffaelli   +8 more
wiley   +1 more source

Transcriptome-Wide Identification of Neuropeptides and Neuropeptide Receptors in the Twenty-Eight-Spotted Ladybird <i>Henosepilachna vigintioctopunctata</i>. [PDF]

Insects
Lei Q, Wang Z, Yao S, Lin A, Zhang Y, Sun C, Liu X, Du M, Liu X, An S.   +9 more
europepmc   +1 more source

Evaluation of the performance of ChatGPT‐4 and ChatGPT‐4o as a learning tool in endodontics

International Endodontic Journal, EarlyView.
Abstract Aims The aim of this study was to evaluate the accuracy and consistency of responses given by two different versions of Chat Generative Pre‐trained Transformer (ChatGPT), ChatGPT‐4, and ChatGPT‐4o, to multiple‐choice questions prepared from undergraduate endodontic education topics at different times of the day and on different days ...
Esra Arılı Öztürk, Ceren Turan Gökduman, Burhan Can Çanakçi   +2 more
wiley   +1 more source

EnsembleNPPred: A Robust Approach to Neuropeptide Prediction and Recognition Using Ensemble Machine Learning and Deep Learning Methods. [PDF]

Life (Basel)
Lertampaiporn S, Wattanapornprom W, Thammarongtham C, Hongsthong A.   +3 more
europepmc   +1 more source

Psychoneuroendocrine stress response in female and male youth with major depressive disorder

Journal of Child Psychology and Psychiatry, EarlyView.
Background Exposure to psychosocial stress is one of the strongest risk factors for major depressive disorder (MDD) in youth, but underlying neurobiological mechanisms are poorly understood. Previous studies on the neuroendocrine stress response in youth with MDD are scarce, limited to cortisol, and rarely considered sex differences.
Anka Bernhard, Nikola Fann, Andreas G. Chiocchetti, Katharina Ackermann, Anne Martinelli, Christine M. Freitag   +5 more
wiley   +1 more source

S100A8/A9 in herpes zoster neuralgia: molecular mechanisms and therapeutic perspectives. [PDF]

Front Immunol
Jiang D, Zhang Z, Ren F, Sun W.
europepmc   +1 more source

Two different G-proteins mediate neuropeptide Y and bradykinin-stimulated phospholipid breakdown in cultured rat sensory neurons

, 1989
T. M. Perney, R. J. Miller
openalex   +1 more source