Results 221 to 230 of about 260,956 (383)

Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions

open access: yesAllergy, EarlyView.
ABSTRACT Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases worldwide. The clinical presentation of AD is heterogeneous and is characterized by a relapsing and remitting course. Most patients suffer from mild AD while approximately 5% to 20% experience severe disease activity, which often requires systemic treatment ...
Marjolein S. de Bruin‐Weller   +9 more
wiley   +1 more source

The sensory penis: A comprehensive immunohistological and ontogenetic exploration of human penile innervation

open access: yesAndrology, EarlyView.
Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani   +6 more
wiley   +1 more source

Phosphatidylinositol‐4,5‐bisphosphate 3‐kinase (PI3K) inhibitors reduce vascular inflammation in vitro and in vivo

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Endothelial cells play central roles in increasing vascular permeability and leukocyte recruitment. Therapeutic approaches for treating endothelial cell barrier dysfunction to reduce unwanted fluid accumulation in tissues are limited.
Hiba Chaudhry   +9 more
wiley   +1 more source

TRPA1 ion channel activation context‐dependently regulates gene expression in normal and psoriatic human skin

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Psoriasis is a chronic, relapsing, immune‐mediated inflammatory skin disease. The transient receptor potential ankyrin 1 (TRPA1) ion channel plays a protective role in the formation of psoriasiform skin reactions. Here, we investigated the pharmacological activation and blockade of TRPA1 in human skin (patho)physiology ...
Ágnes Kemény   +10 more
wiley   +1 more source

Enzyme‐linked immunosorbent assay for the neuropeptide ‘head activator’ [PDF]

open access: bronze, 1984
Hubert Schaller   +3 more
openalex   +1 more source

Home - About - Disclaimer - Privacy