Results 271 to 280 of about 266,484 (376)
Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska +8 more
wiley +1 more source
Corneal sensory nerve loss induced by repeated subconjunctival and topical bupivacaine disrupts tear secretion and enhances bacterial adhesion via neuropeptide modulation. [PDF]
Datta A, Orallo GK, Nelson N.
europepmc +1 more source
The exposomal imprint on rosacea: More than skin deep
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki +3 more
wiley +1 more source
Conventional ambient temperature housing impacts central oxytocin levels in mice. [PDF]
Kenkel WM +3 more
europepmc +1 more source
Therapeutic advances in pruritus as a model of personalized medicine
Recent advances in itch biology reveal that chronic pruritus arises from distinct neuroimmune pathways driven by cytokines, JAK, BTK and GPCRs. Targeted biologics and small molecule inhibitors such as dupilumab, nemolizumab, remibrutinib and JAK inhibitors precisely modulate these pathways, leading to a new era of personalized therapeutics in pruritus.
Kelsey Auyeung +2 more
wiley +1 more source
Regulation of granin neuropeptide gene expression in human brain during development. [PDF]
Demsey LL, Podvin S, Hook V.
europepmc +1 more source
Serotonin and the Neuropeptide PDF Initiate and Extend Opposing Behavioral States in C. elegans
S. Flavell +5 more
semanticscholar +1 more source

