Results 281 to 290 of about 266,484 (376)

Neural modulation of ocular immunity: Exploring a sympathetic‐macrophage neuroimmune link in the human ciliary body

Journal of Anatomy, EarlyView.
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou, Claire Mackaaij, Mark van Zijverden, Hendrik A. Messal, Jeannette Ossewaarde‐van Norel, Ronald L. A. W. Bleys, Cindy G. J. Cleypool   +6 more
wiley   +1 more source

The relationship of temperamental, biochemical trait variables determining appetitive behaviour and alcohol-dependent individuals' health status and nutrition - preliminary study. [PDF]

Postep Psychiatr Neurol
Czarnecki D, Chodkiewicz J, Długosz A, Budzyński J, Marszałł MP, Waszkiewicz N, Kułak-Bejda A, Gorzkiewicz M, Junkiert-Czarnecka A, Michalska M, Żekanowska E, Ziółkowski M.   +11 more
europepmc   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, EarlyView.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Fine-Tuning of the Neuropeptide Y1 G Protein-Coupled Receptor by the Tryptophan^6.48 "Toggle Switch". [PDF]

J Am Chem Soc
Voitel M, Pankonin M, Vogel A, Leitner K, Kaiser A, Huster D, Hildebrand PW, Smith AA.   +7 more
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Ketogenic diet-induced changes in methylation status and neuropeptide signaling: relationships between S-adenosylmethionine (AdoMet), orexin-A, and metabolic health. [PDF]

Front Physiol
Mosca L, Monda A, Messina A, Cadoni F, Moscatelli F, La Marra M, Monda V, Di Maio G, Allocca S, Casella C, Casillo M, Polito R, Monda M, Porcelli M, Messina G.   +14 more
europepmc   +1 more source

Neuropeptide Y in the central nucleus of the amygdala suppresses dependence-induced increases in alcohol drinking

, 2008
Nicholas W. Gilpin, Kaushik Misra, George F. Koob   +2 more
openalex   +1 more source

The Association Between Disordered Eating and Sleep in Non‐Clinical Populations—A Systematic Review and Meta‐Analysis

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep and disordered eating behaviours may be linked through physiological and psychological mechanisms; yet, no review has systematically investigated the relationship between different sleep indicators and disordered eating behaviours and cognitions outside a clinical context.
Marie‐Christine Opitz, Nora Trompeter, Francisco Diego Rabelo‐da‐Ponte, Michelle Carroll, Kyle Buchan, Giulia Gaggioni, Sarah Moody, Sylvane Desrivières, Nadia Micali, Ulrike Schmidt, Helen Sharpe, EDIFY Consortium, Ulrike Schmidt, Helen Sharpe, Karina Allen, Heike Bartel, Iain Campbell, Sylvane Desrivières, Richard Dobson, Amos Folarin, Tara French, John Kelly, Umairah Malik, Nadia Micali, Sneha Raman, Zulqarnain Rashid, Janet Treasure, Callum Bryson, Daire Douglas, Amelia Hemmings, Başak İnce Çağlar, Carina Kuehne, Sarah Moody, Marie‐Christine Opitz, Tamsin Parnell, Fiona Stephens, Nora Trompeter, Jessica Wilkins, Alice Bromell, Grace Davis, Cameron Eadie, Beck Heslop, Isabella Malvisi, Katie Mckenzie, Emma Scott, Chris Sims, Tallulah Street, Andreia Tavares‐Semedo, Eleanor Wilkinson, Lucz Zocek   +49 more
wiley   +1 more source

Short Communication: The Neuropeptide Substance P Mediates Adventitial Mast Cell Activation and Induces Intraplaque Hemorrhage in Advanced Atherosclerosis

, 2009
Ilze Bot, Saskia C.A. de Jager, Martine Bot, Sandra H. van Heiningen, Paul de Groot, Roel W. Veldhuizen, Theo J.C. van Berkel, Jan H. von der Thüsen, Erik A.L. Biessen   +8 more
openalex   +2 more sources

Corticotropin‐Releasing Hormone (CRH) in Murine Narcolepsy: What Do Genetic and Immune Models Tell Us?

Journal of Sleep Research, EarlyView.
ABSTRACT Narcolepsy type 1 is a chronic sleep disorder of putative autoimmune aetiology, primarily caused by the loss of orexin‐producing neurons in the hypothalamus. An additional 88% reduction in corticotropin‐releasing hormone‐immunoreactive neurons of the paraventricular nucleus has been recently observed in post‐mortem brains of individuals with ...
J. Zhou, S. Melzi, A. L. Morel, B. Georges, T. E. Scammell, G. J. Lammers, R. Fronczek, C. Peyron   +7 more
wiley   +1 more source