Results 291 to 300 of about 221,321 (383)

Targeting Neuropeptide Receptors for Cancer Imaging and Therapy: Perspectives with Bombesin, Neurotensin, and Neuropeptide-Y Receptors

open access: yesJournal of Nuclear Medicine, 2014
C. Morgat   +5 more
semanticscholar   +1 more source

Exploring neuronal mechanisms of osteosarcopenia in older adults

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley   +1 more source

Somatostatin modulation of initial fusion pores in Ca2+‐triggered exocytosis from mouse chromaffin cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Somatostatin binds to a G‐protein‐coupled receptor to inhibit the release of catecholamine from chromaffin cells. This action has no impact on Ca2+ levels and is similar for Ca2+ entry through voltage‐gated Ca2 channels and for Ca2+ mobilization from the endoplasmic reticulum.
Jinbo Cheng, Meyer B. Jackson
wiley   +1 more source

Incretin hormones and obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The incretin system in obesity. The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) (yellow) and glucagon‐like peptide‐1 (GLP‐1) (blue) are produced by the proximal and distal small intestinal epithelium, where they are released postprandially into the bloodstream to modulate a myriad of physiological and ...
Constanza Alcaino   +2 more
wiley   +1 more source

Activation of TRPA1 and TRPM3 triggers Ca2+ waves in central terminals of sensory neurons and facilitates synaptic activity in the spinal dorsal horn

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Transient receptor potential ankyrin 1 (TRPA1) and melastatin 3 (TRPM3) activation regulate pre‐ and postsynaptic Ca2+ concentrations and synaptic activity in the dorsal horn of the spinal cord. Left: a model that describes how activation of TRPA1 and TRPM3 channels induces an influx of Ca2+ in the central terminals of sensory ...
Yaroslav E. Andrianov   +10 more
wiley   +1 more source

Loss of neuropeptidergic regulation of cholinergic transmission induces homeostatic compensation in muscle cells to preserve synaptic strength. [PDF]

open access: yesPLoS Biol
Shao J   +7 more
europepmc   +1 more source

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