Amyloid β induces hormetic-like effects through major stress pathways in a C. elegans model of Alzheimer's Disease. [PDF]
Lichty JD, Mane H, Yarmey VR, Miguel AS.
europepmc +1 more source
Chondrodystrophic Dogs as a Preclinical Large Animal Model of Discogenic Back Pain
This study aims to validate an underutilized canine preclinical model of discogenic back pain model by deep phenotyping several structural and pain associated outcomes with novel findings in the areas of RNA sequencing and whole patch clamp of canine dorsal root ganglion neurons.
Mary K. Heimann+18 more
wiley +1 more source
TDP-43 overexpression in the hypothalamus drives neuropathology, dysregulates metabolism and impairs behavior in mice. [PDF]
Bergh S+7 more
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The differences in local translatome across distinct neuron types is mediated by both baseline cellular differences and post-transcriptional mechanisms [PDF]
Aryal, Shivani+4 more
core +1 more source
ABSTRACT This review presents a comprehensive synthesis of research on yellowtail kingfish (Seriola lalandi) aquaculture, with a particular focus on production in recirculating aquaculture systems (RAS). Significant progress has been made in reproductive biology and captive spawning, which are critical for ensuring a reliable juvenile supply.
Alexander Chong Shu‐Chien+8 more
wiley +1 more source
Beyond the Binary: Controlling Natural Sex‐Change in Hermaphroditic Fishes
ABSTRACT Sex‐change in hermaphroditic fishes is a complex but natural biological phenomenon that has significant implications for aquaculture fingerling production, selective breeding, and grow‐out. Understanding the physiological, endocrinological, and molecular pathways underlying hermaphroditism in fishes offers unique opportunities to manipulate ...
Roni Chandra Mondal+3 more
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Sensory and Autonomic Fibers in Anterior Ethmoid, Posterior Nasal, Posterolateral Nasal Nerves. [PDF]
Craig JR+6 more
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Physics of Protein Aggregation in Normal and Accelerated Brain Aging
Soluble monomeric proteins precipitate via nucleation into insoluble amyloids in response to age‐related exposures (e.g., microbes, nanoparticles). Persistent soluble‐to‐insoluble phase transition depletes the functional proteins. In normal aging, replacement matches loss; in accelerated aging, it does not.
Alberto J. Espay+9 more
wiley +1 more source
A brief discussion on the role of calcitonin gene-related peptide in the efficacy of rehabilitation medicine. [PDF]
Zhencheng G, Aiguo X.
europepmc +1 more source