Results 311 to 320 of about 260,956 (383)
Expanding our understanding of (mal)adapted stress physiology in psychiatric disorders: achieving single-cell characterisation of steroids and neuropeptides. [PDF]
Neurobiol StressEdmond KZ, Matosin N.
europepmc +1 more source
The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies
Obesity Reviews, EarlyView.ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin +6 more
wiley +1 more source
Mapping and decoding neuropeptide signaling networks in nervous system function.
Curr Opin NeurobiolBeets I, Watteyne J.
europepmc +1 more source
Obesity Reviews, EarlyView.ABSTRACT Polycystic ovary syndrome (PCOS) is a common endocrine disorder with a complex pathogenesis that includes disordered follicle development, hypothalamic–pituitary–ovarian (HPO) axis dysfunction, hyperandrogenemia, and insulin resistance. The risk of complications during pregnancy, such as gestational diabetes mellitus (GDM) and preeclampsia (PE)
Shaohua Zhang +5 more
wiley +1 more source
Contribution of Sympathetic Sensory Coupling to Craniofacial Nociception
Orthodontics &Craniofacial Research, EarlyView.ABSTRACT Stress and anxiety are associated with increased pain intensity in temporomandibular disorders (TMDs) patients. It is possible that this association is due to a direct interaction between the sympathetic and sensory nervous systems. This narrative review examines evidence for a potential sympathetic sensory interaction in deep craniofacial ...
Brian Edwin Cairns
wiley +1 more source
Orthodontics &Craniofacial Research, EarlyView.ABSTRACT Objective Sympathetic‐sensory coupling is increasingly implicated in joint homeostasis and disease. Towards the long‐term goal of deciphering its role in temporomandibular disorders (TMDs), we characterised the spatial relationships of sympathetic and sensory nerves and their receptors in the mouse temporomandibular joint (TMJ) and trigeminal ...
Qianlin Ye +4 more
wiley +1 more source
Differentially Expressed Salivary miRNAs in Temporomandibular Disorders
Orthodontics &Craniofacial Research, EarlyView.ABSTRACT Objective Temporomandibular disorders (TMDs) are heterogeneous conditions of unclear aetiology involving the temporomandibular joint, masticatory muscles and neural tissues. Limited understanding of their pathogenesis hampers accurate diagnosis and targeted treatment. Therefore, this study aimed to identify salivary microRNA (miRNA) signatures
Karolina Elżbieta Kaczor‐Urbanowicz +13 more
wiley +1 more source
Pain Phenotype in Knee Osteoarthritis: Implications for Mechanism‐Based Therapy
Orthopaedic Surgery, EarlyView.The paper reported on the precise and individual treatment of knee osteoarthritis (KOA) pain based on its new classification, including Nociceptive Pain, Neuropathic Pain, and Nociplastic Pain. Tailored treatment recommendations for different types of pain through exploring potential mechanisms of pain in KOA are provided to achieve better clinical ...
Chenchang He +5 more
wiley +1 more source