Results 81 to 90 of about 260,956 (383)

The Neuropeptide Cortistatin Alleviates Neuropathic Pain in Experimental Models of Peripheral Nerve Injury

open access: yesPharmaceutics, 2021
Neuropathic pain is one of the most severe forms of chronic pain caused by the direct injury of the somatosensory system. The current drugs for treating neuropathies have limited efficacies or show important side effects, and the development of ...
Clara P. Falo   +9 more
doaj   +1 more source

Neuropeptides in tendinopathy [PDF]

open access: yesFrontiers in Bioscience, 2009
Overuse tendinopathy remains a major clinical burden for sports medicine and general practitioners. Recent studies have highlighted the role of sensory and autonomic nerves in generating or perpetuating the symptoms and tissue abnormalities associated with tendinopathy.
Roald Bahr, Alex Scott
openaire   +3 more sources

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao   +2 more
wiley   +1 more source

Neuropeptide signals cell non-autonomous mitochondrial unfolded protein response

open access: yesCell Research, 2016
Neurons have a central role in the systemic coordination of mitochondrial unfolded protein response (UPRmt) and the cell non-autonomous modulation of longevity.
Li-Wa Shao, R. Niu, Ying Liu
semanticscholar   +1 more source

VEGF Axonal Transport Dependent on Kinesin-1B and Microtubules Dynamics

open access: yesFrontiers in Molecular Neuroscience, 2017
Axon-transport plays an important role in neuronal activity and survival. Reduced endogenous VEGF can cause neuronal damage and axon degeneration. It is unknown at this time if VEGF can be transported within the axon or whether it can be released by ...
Ping Yang   +6 more
doaj   +1 more source

Neuroimmune Microenvironment Reprogramming via Immuno‐piezoelectric Transducers for Synergistic Stem Cell Therapy in Traumatic Brain Injury

open access: yesAdvanced Materials, EarlyView.
A novel immuno‐piezoelectric transducer is innovatively developed. This device promotes neural stem cell (NSC) differentiation and maturation via ultrasound‐induced electrical stimulation and it amplifies the therapeutic efficacy of NSC in traumatic brain injury (TBI) by modulating the immune microenvironment. This piezoelectric transducer with “immune‐
Linlin Liang   +12 more
wiley   +1 more source

Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila

open access: yesNature Communications, 2017
Animal circadian clocks consist of central and peripheral pacemakers, which are coordinated to produce daily rhythms in physiology and behaviour. Despite its importance for optimal performance and health, the mechanism of clock coordination is poorly ...
M. Selcho   +10 more
semanticscholar   +1 more source

Homeostasis in C. elegans sleep is characterized by two behaviorally and genetically distinct mechanisms

open access: yeseLife, 2014
Biological homeostasis invokes modulatory responses aimed at stabilizing internal conditions. Using tunable photo- and mechano-stimulation, we identified two distinct categories of homeostatic responses during the sleep-like state of Caenorhabditis ...
Stanislav Nagy   +6 more
doaj   +1 more source

Identification, Characterization, and Expression of a PRQFVamide-Related Peptide in Cephalopod Sepiella japonica

open access: yesFrontiers in Marine Science, 2022
Neuropeptides, as neurotransmitters and neuromodulators, have a variety of physiological functions in the mollusk. Here, a PRQFVamide-related peptide gene was cloned from cuttlefish Sepiella japonica (designated as SjPRQFVRP, GenBank Accession No ...
Jia-yin Qiu   +2 more
doaj   +1 more source

Neuropeptide S [PDF]

open access: yesNeuron, 2004
Arousal and anxiety are behavioral responses that involve complex neurocircuitries and multiple neurochemical components. Here, we report that a neuropeptide, neuropeptide S (NPS), potently modulates wakefulness and could also regulate anxiety. NPS acts by activating its cognate receptor (NPSR) and inducing mobilization of intracellular Ca2+.
Luis de Lecea   +11 more
openaire   +3 more sources

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