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Introduction to the reviews on neuropeptide Y
Neuropeptides, 2004Neuropeptide Y (NPY) was first reported as an abundant peptide in brain tissue in 1982. Shortly thereafter, NPY was found to be a member of a peptide family consisting of the endocrine peptides pancreatic polypeptide (PP) and peptide YY (PYY). These peptides exert most of their biological effects through five G-protein coupled receptors termed Y1, Y2 ...
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Renal effects of neuropeptide Y
Pfl�gers Archiv European Journal of Physiology, 1998Neuropeptide Y (NPY) is a co-transmitter of the sympathetic nervous system including the renal nerves. The kidney expresses NPY receptors, which can also be activated by peptide YY (PYY), a circulating hormone released from gastrointestinal cells. Five subtypes of NPY receptors have been cloned, among which Y1, Y2 and Y5 appear to be involved in the ...
Angela Bischoff, Martin C. Michel
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Drug Development Research, 1990
AbstractNeuropeptide Y (NPY) has a broad distribution and numerous physiological functions in the peripheral and central nervous systems. The gene transcription and fundamentals of peptide processing have been elucidated. NPY levels and release are exquisitely sensitive to pharmacological and physiological manipulation.
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AbstractNeuropeptide Y (NPY) has a broad distribution and numerous physiological functions in the peripheral and central nervous systems. The gene transcription and fundamentals of peptide processing have been elucidated. NPY levels and release are exquisitely sensitive to pharmacological and physiological manipulation.
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Neuropeptide Y and Sympathetic Neurotransmissiona
Annals of the New York Academy of Sciences, 1990The coexistence of neuropeptide Y (NPY) with noradrenaline (NA) in perivascular nerves as well as in sympathetic nerves to muscle in the heart, spleen and vas deferens suggests a role for NPY in autonomic transmission. Sympathetic nerve stimulation or reflexogenic activation in experimental animals or man are associated with NPY release as revealed by ...
Anders Franco-Cereceda +3 more
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Neuropeptide Y receptor subtypes
Life Sciences, 1995Neuropeptide Y (NPY) is an amidated 36-amino acid peptide with a wide distribution in the central and peripheral nervous system. It can evoke numerous physiological responses by activating specific receptors. Studies using NPY analogs in various model systems and cell types demonstrate different orders of ligand potency and receptor binding affinity ...
Chok P. Wan, Benjamin H.S. Lau
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Neuropeptide Y and the cerebral circulation
2006The presence of NPY receptors on both endothelial and vascular smooth muscle cells indicates that blood-borne NPY as well as NPY stemming from surrounding nerves can affect contractile responses of cerebral vessels. In addition, endothelial cells may themselves be a source of NPY as well as a site of NPY metabolism.
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Neuropeptide Y: the universal soldier
Cellular and Molecular Life Sciences CMLS, 2003The peptidic neuropeptide Y (NPY) has received great attention because it has been implicated in the regulation of several organ systems. In particular, NPY is involved in the regulatory loops that control food intake in the hypothalamus and appears also to be important for regulating the activity of neuroendocrine axes under poor metabolic conditions.
Eric Grouzmann +2 more
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NEUROPEPTIDE Y AND CARDIOVASCULAR REGULATION
Clinical and Experimental Pharmacology and Physiology, 1991SUMMARY1. The effects of neuropeptide Y (NPY) and related peptide fragments on blood pressure and vagal action at the heart were compared in the anaesthetized rat.2. A change in vagal action was taken as a measure of presynaptic activity and a change in blood pressure was taken as a measure of postsynaptic activity.3.
D I McCloskey, Erica K. Potter
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2000
Part I. Cloning Techniques. Cloning Neuropeptide Tyrosine cDNA, Carolyn A. Worby. Human Y1/Y5 Receptor Gene Cluster: Isolation and Characterization, Herbert Herzog. Human Type 2 Neuropeptide Y Receptor Gene: Isolation and Characterization, David A. Ammar and Debra A. Thompson.
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Part I. Cloning Techniques. Cloning Neuropeptide Tyrosine cDNA, Carolyn A. Worby. Human Y1/Y5 Receptor Gene Cluster: Isolation and Characterization, Herbert Herzog. Human Type 2 Neuropeptide Y Receptor Gene: Isolation and Characterization, David A. Ammar and Debra A. Thompson.
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2004
Neuropeptide Y (NPY) is a co-transmitter of the sympathetic nervous system including the renal nerves. The kidney expresses NPY receptors, which can also be activated by peptide YY (PYY), a circulating hormone released from gastrointestinal cells. Five subtypes of NPY receptors have been cloned, among which Y1, Y2and Y5 appear to be involved in the ...
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Neuropeptide Y (NPY) is a co-transmitter of the sympathetic nervous system including the renal nerves. The kidney expresses NPY receptors, which can also be activated by peptide YY (PYY), a circulating hormone released from gastrointestinal cells. Five subtypes of NPY receptors have been cloned, among which Y1, Y2and Y5 appear to be involved in the ...
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