Results 201 to 210 of about 212,465 (393)

Disease Modification by Combinatorial Single Vector Gene Therapy: A Preclinical Translational Study in Epilepsy

Molecular Therapy: Methods & Clinical Development, 2019
Gene therapy has been suggested as a plausible novel approach to achieve seizure control in patients with focal epilepsy that do not adequately respond to pharmacological treatment.
Esbjörn Melin, Avtandil Nanobashvili, Una Avdic, Casper R. Gøtzsche, My Andersson, David P.D. Woldbye, Merab Kokaia   +6 more
doaj  

Neuropeptide Y Inhibits the Biosynthesis of Sulfated Neurosteroids in the Hypothalamus through Activation of Y1 Receptors [PDF]

, 2002
Delphine Beaujean
openalex   +2 more sources

A GLP‐1R/Y1 receptor/Y2 receptor triple agonist decreases fentanyl‐evoked dopamine release in the nucleus accumbens and attenuates fentanyl taking and seeking in rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Emerging literature indicates that simultaneously targeting glucagon‐like peptide‐1 receptors (GLP‐1Rs) and neuropeptide Y receptors (Y1/Y2) may represent a new pharmacotherapeutic approach to treating opioid use disorder (OUD).
Antonia Caffrey, Enzo Lavecchia, Kylie S. Chichura, Matthew R. Hayes, Robert P. Doyle, Heath D. Schmidt   +5 more
wiley   +1 more source

Vascular pharmacology of BIIE0246, the first selective non‐peptide neuropeptide Y Y₂ receptor antagonist, in vivo [PDF]

, 2001
Rickard E. Malmström
openalex   +1 more source

Regenerating Locus Coeruleus‐Norepinephrine (LC‐NE) Function: A Novel Approach for Neurodegenerative Diseases

Cell Proliferation, EarlyView.
The regeneration of LC‐NE from pluripotent stem cells (PSCs) could significantly mitigate the progression of Neurodegenerative diseases and alleviate associated psychiatric disease symptoms, providing a new approach to the treatment of neurological diseases.
Yana Yang, Yunlong Tao
wiley   +1 more source

Neuropeptide Y receptor activation preserves inner retinal integrity through PI3K/Akt signaling in a glaucoma mouse model. [PDF]

PNAS Nexus
Palanivel V, Gupta V, Chitranshi N, Tietz O, Vander Wall R, Blades R, Maha Thananthirige KP, Salkar A, Shen C, Mirzaei M, Gupta V, Graham SL, Basavarajappa D.   +12 more
europepmc   +1 more source

The property of larval cells of the scleractinian coral, Acropora tenuis, deduced from in vitro cultured cells

Development, Growth &Differentiation, Volume 67, Issue 3, Page 119-135, April 2025.
Using antibodies raised against in vitro cultured cells, we determined the property of coral larval cells. Neuronal cells, ectoderm cells, and endoderm cells were characterized. Abstract In previous studies, we have established approximately 15 cultured cell‐lines derived from planula larvae of Acropora tenuis.
Kaz Kawamura, Satoko Sekida, Koki Nishitsuji, Noriyuki Satoh   +3 more
wiley   +1 more source

Neuropeptide Y receptor 1 and galanin receptor 2 (NPY1R-GALR2) interactions in the dentate gyrus and their relevance for neurogenesis and cognition. [PDF]

Front Cell Neurosci
Beltran-Casanueva R, Hernández-García A, de Amo García P, Blanco-Reina E, Serrano-Castro P, García-Casares N, Fuxe K, Borroto-Escuela DO, Narváez M.   +8 more
europepmc   +1 more source

Molecular characterization of the neuropeptide Y Y₂₋receptor [PDF]

, 1998
openaire   +2 more sources

Neuroprotection for neonatal hypoxic–ischemic encephalopathy: A review of novel therapies evaluated in clinical studies

Developmental Medicine &Child Neurology, Volume 67, Issue 5, Page 591-599, May 2025.
Hypoxic‐ischemic encephalopathy (HIE) is a neurologic condition that is caused by insufficient oxygen and blood flow to a newborn infant’s brain. Although therapeutic hypothermia can reduce the degree of brain injury in some infants with HIE, many infants with HIE will have significant lifelong disabilities despite receiving this treatment.
Natalie H. Chan, Cheryl C. Hawkins, Benjamin V. Rodrigues, Marie‐Coralie Cornet, Fernando F. Gonzalez, Yvonne W. Wu   +5 more
wiley   +1 more source