Results 121 to 130 of about 72,976 (300)

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Inflammation changes the expression of neuropeptide Y receptors in the pig myometrium and their role in the uterine contractility. [PDF]

PLoS One, 2020
Jana B, Całka J, Palus K.
europepmc   +1 more source

Molecular Aspect of Annelid Neuroendocrine system

, 2007
Hormonal processes along with enzymatic processing similar to that found in vertebrates occur in annelids. Amino acid sequence determination of annelids precursor gene products reveals the presence of the respective peptides that exhibit high sequence ...
Salzet, M.
core   +1 more source

Anuran call properties as reliable indicators of environmental suitability for reproduction

Frontiers in Ecology and the Environment, EarlyView.
The onset of animal breeding activity is often accompanied by auditory signals, typically produced by males, that indicate reproductive status to potential mates and competitors. Here, using male anuran advertisement calls as a case study, we present the novel hypothesis that characteristics of ectotherm auditory signals that are modulated by ...
Julianne E Pekny, Brian D Todd, Eric Post   +2 more
wiley   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Neuromedin U partially mediates leptin-induced hypothalamo-pituitary adrenal (HPA) stimulation and has a physiological role in the regulation of the HPA axis in the rat.

, 2006
Intracerebroventricular (ICV) administration of the hypothalamic neuropeptide neuromedin U (NMU) or the adipostat hormone leptin increases plasma ACTH and corticosterone.
Abbott, CR, Bloom, SR, Darch, SJ, Ghatei, MA, Jethwa, PH, Murphy, KG, Patel, SR, Semjonous, NM, Seth, A, Small, CJ, Smith, KL, Todd, JF   +11 more
core   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Neuropeptide Y neurons mediate opioid-induced itch by disinhibiting GRP-GRPR microcircuits in the spinal cord

Nature Communications
Itch is a common side effect of opioid analgesics. The specific neurons mediating opioid-induced itch are still debated, and the mechanistic neuronal circuits remain elusive.
Qian Zeng, Yitong Li, Yifei Wu, Jiawei Wu, Kangtai Xu, Yiming Chen, Yunfei Rao, Nan Li, Yuhui Luo, Changyu Jiang, Chaoran Wu, Zilong Wang   +11 more
doaj   +1 more source

ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In rotifers, ParaHox genes show a dispersed genomic organization, with Xlox absent across gnathiferans. Exclusive neuronal expression of Gsx and Cdx reveals that ancestral ParaHox genes coordinated neural and epithelial development beyond gut patterning, suggesting an integrated role in early bilaterian body plan organization.
Andreas C. Fröbius, David B. Mark Welch, Holger Herlyn   +2 more
wiley   +1 more source

Targeting NPY5R—A Member of the NPY Receptor Family: Pharmacological and Transcriptomic Mechanisms of the Euphorbia Factor L2 Against Lung Adenocarcinoma

Pharmaceuticals
Background: Advanced lung adenocarcinoma (LUAD) is the leading cause of cancer-related deaths, with existing treatments hampered by drug resistance. This underscores the urgent need to identify novel therapeutic targets.
Pengzhuo Tao, Wei Liu, Yongfu Wang, Yajing Xue, Changmin Liu, Yizhen Yuan, Kim Fey Leu, Shilin Chen, Chi Song   +8 more
doaj   +1 more source