Results 131 to 140 of about 21,634,263 (295)
, 1994 Since the discovery of neuropeptide Y which is co-stored and co-operate with noradrenaline (NA) in sympathetic nerve fibers, several scientific groups have searched for structures with neuropeptide Y antagonistic properties.
Edvinsson, Lars +7 more
core +1 more source
Tissue Clearing for Lymph Nodes: 3D Mapping of Nerves and the Immune Microenvironment
iNew Medicine, EarlyView.ABSTRACT Lymph nodes (LNs) are central hubs of adaptive immunity and key relay sites for metastatic tumour cells. However, conventional two‐dimensional histology samples only a small fraction of each node, potentially missing micrometastases and multifocal involvement while obscuring long‐range spatial relationships among tumour deposits, immune ...
Guang‐Hong Su +7 more
wiley +1 more source
Nociceptin/orphanin FQ and motor activity: behavioural, biochemical and electrophysiological studies in models of Parkinson’s disease [PDF]
, 2010 Nociceptin/orphanin FQ (N/OFQ) is an opioid-like neuropeptide which activates the NOP receptor. N/OFQ exerts an inhibitory control on locomotion through inhibition of dopamine (DA) neurons located in the substantia nigra (SN), which degenerate in ...
Viaro, Riccardo
core
Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases
Phytotherapy Research, EarlyView.Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin +7 more
wiley +1 more source
Energy homeostasis : crosstalk between adipose tissue and the human hypothalamus [PDF]
There is a worldwide epidemic of obesity. Weight rise is a consequence of continuous positive energy balance which leads to accumulation of body fat. Recent insights into adipose tissue (AT) biology have led to the conclusion that the adipocyte is not
Kos, Katarina
core
Research Progress on Upper Airway Cough Syndrome
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley +1 more source
Cytoskeletal inhibitors impair Ca2+ elevations via neuropeptide Y and other Gi-coupled receptors
, 1996 Neuropeptide Y, alpha 2-adrenoceptors, thrombin and certain muscarinic acetylcholine receptors can couple to elevations of intracellular free Ca2+ concentrations via Gi-proteins.
Kaldenberg-Stasch, S. +5 more
core +1 more source
PLoS ONENeuropeptide Y-related signaling, consisting of various neuropeptides and their receptors including, for example, the mammalian neuropeptide Y (NPY), pancreatic polypeptide (PP), and peptide YY (PYY) families, along with neuropeptide Y-like peptides in ...
Jinghan Tan +2 more
doaj +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li +12 more
wiley +1 more source
Techniques in Neuropeptide Processing, Trafficking, and Secretion
, 2007 Neuropeptides function as neurotransmitters and neuromodulators. They are synthesized as larger precursors at the rough endoplasmic reticulum (RER), trafficked to the trans-Golgi network (TGN), and sorted into granules of the regulated secretory pathway (
Nimesh Patel +11 more
core +1 more source