Results 181 to 190 of about 72,976 (300)
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Semaglutide is a GLP‐1 receptor agonist for the treatment of type 2 diabetes and obesity. Its clinical effects are well established, but the underlying mechanisms remain unclear. This study aims to use computational modelling to generate hypotheses about semaglutide's long‐term metabolic (body weight, net energy intake, blood glucose ...
Vivan C. W. Kennis, Natal A. W. van Riel
wiley +1 more source
Meningeal neuropeptide and neuroimmune interactions in the context of migraine. [PDF]
J Headache PainAdi T, Gold MS.
europepmc +1 more source
Entomologia Experimentalis et Applicata, EarlyView.We evaluated Lasiocampa quercus as an overwintering host for the koinobiont larval endoparasitoid Glyptapanteles porthetriae by exposing parasitized larvae to different environmental conditions and comparing parasitoid development with that in the primary host Lymantria dispar.
Thomas Zankl, Christa Schafellner
wiley +1 more source
The Involvement of the Peptidergic Systems in Breast Cancer Development. [PDF]
Cancers (Basel)Sánchez ML +5 more
europepmc +1 more source
Reversible cerebral vasoconstriction syndrome: A narrative review
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objectives/Background This review summarizes current insights into Reversible cerebral vasoconstriction syndrome (RCVS) diagnosis, management, and outcomes. RCVS is a cerebrovascular disorder characterized by recurrent thunderclap headaches and transient segmental vasoconstriction of cerebral arteries, typically resolving within 3 months ...
Ícaro Araújo de Sousa +7 more
wiley +1 more source
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objective To highlight key factors required to optimize multi‐mechanistic approaches with oral combination treatments for the acute management of a migraine attack. Background Given the complex multi‐factorial nature of migraine, combining treatments with different mechanisms of action should improve outcomes compared to monotherapies, but ...
Stephen Silberstein, Alan M. Rapoport
wiley +1 more source
An exploratory microarray analysis of estrogen-mediated gene expression in central pathways that control energy balance in female rats (Rattus norvegicus). [PDF]
BMC Res NotesLang H, Burch K, Sloan D.
europepmc +1 more source
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objective Calcitonin gene‐related peptide (CGRP) inhibitors, including monoclonal antibodies (mAbs) and small‐molecule antagonists (gepants), have transformed migraine treatment. Although clinical trials established their efficacy and initial safety, post‐marketing surveillance is essential for understanding their real‐world safety profile in ...
Martina Giacon, Salvatore Terrazzino
wiley +1 more source
Glucose Intake during the Neonatal Period Modulates the Central Melanocortin System with Breed-Specific Differences. [PDF]
J Poult SciKimura K +6 more
europepmc +1 more source
Delayed urticaria during treatment with anti‐CGRP monoclonal antibodies in migraine
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objective To characterize clinical presentation and management of urticaria associated with calcitonin gene‐related peptide (CGRP) ‐targeting monoclonal antibodies (mAbs) for migraine prophylaxis. Background CGRP‐targeting mAbs are effective in migraine prophylaxis, but have been associated with hypersensitivity reactions, including urticaria.
Christoph T. Berger +5 more
wiley +1 more source