Results 101 to 110 of about 74,693 (295)

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag   +14 more
wiley   +1 more source

Ectopic expression of the neuropeptide pigment-dispersing factor alters behavioral rhythms in Drosophila melanogaster.

open access: green, 2000
Charlotte Helfrich‐Förster   +5 more
openalex   +2 more sources

The Second Hit Hypothesis in Animal and Human Dystonia: The Role of Peripheral Nerve Trauma and Spinal Cord Injury

open access: yesMovement Disorders, EarlyView.
The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger   +1 more
wiley   +1 more source

Neuronal Reshaping of the Tumor Microenvironment in Tumorigenesis and Metastasis: Bench to Clinic

open access: yesMedicine Advances, EarlyView.
This graphical abstract illustrates the multidimensional crosstalk between neurons and tumor microenvironment as well as targeted intervention strategies identified in the study. It highlights three core interaction axes: nerve‐tumor crosstalk mediated by neurotransmitters and neurotrophic factors, neuro‐vascular communication driving angiogenesis via ...
Yimao Wu   +4 more
wiley   +1 more source

Should We Consider Sacral Nerve Stimulation as a Treatment for Neurogenic Lower Urinary Tract Dysfunction? ICI‐RS 2025

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims To explore the boundary of clinical use of sacral nerve stimulation (SNS) in neurogenic lower urinary tract dysfunction (NLUTD), identifying barriers to approval and early‐impact research questions. Methods This review is derived from a proposal discussion at the International Consultation on Incontinence‐Research Society in Bristol in ...
Marcus J. Drake   +6 more
wiley   +1 more source

Neuropeptide W facilitates chronic gastric ulcer healing by the regulation of cyclooxygenase and NF-κB signaling pathways [PDF]

open access: hybrid
Sevil Arabacı Tamer   +6 more
openalex   +1 more source

The neuropeptide concept

open access: yesMaturitas, 1984
In 1960/61 it was found that the release of adrenocorticotrophic hormone (ACTH) in response to emotional, but not to somatic or systemic stress, was diminished in rats in which the vasopressin storage organ, the posterior intermediate lobe of the rat pituitary, had been surgically removed [1,2].
openaire   +4 more sources

Regulatory mechanisms of reproduction in locusts and grasshoppers

open access: yesNew Plant Protection, EarlyView.
Regulatory networks composed of numerous coding and noncoding genes play crucial roles in the reproduction of locusts and grasshoppers. This review integrates mechanistic advances in reproductive regulation, highlighting environmentally adaptive pathways and providing prospective targets for eco‐friendly pesticides.
Jing He, Jiliang Wang, Xinran Wang
wiley   +1 more source

Mechanisms Attenuating Cellular Responses to Neuropeptides: Extracellular Degradation of Ligands and Desensitization of Receptors

open access: bronze, 1997
Eileen F. Grady   +6 more
openalex   +1 more source

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