Results 101 to 110 of about 73,747 (293)
Obesity, EarlyView.ABSTRACT Objective Topiramate is a medication used off‐label, or in combination with phentermine, for the management of obesity. However, its mechanism of action remains elusive. As many obesity medications target the brain, we aimed to determine if topiramate influences the activity of hypothalamic melanocortin neurons known to regulate energy balance.
Moein Minbashi Moeini +4 more
wiley +1 more source
Antipruritic vs. Antitumour Action of Aprepitant: A Question of Dose
Acta Dermato-Venereologica, 2019 Miguel Muñoz +3 more
doaj +1 more source
Inhibition of cardiac vagal effects by neurally released and exogenous neuropeptide Y. [PDF]
, 1989 Margaret R. Warner, Matthew N. Levy
openalex +1 more source
Nectar concentrations of biogenic amines affect bumble bee behavior in a dose‐dependent manner
Oikos, EarlyView.While foraging, pollinators encounter a wide array of molecules, some of which may influence their internal states and behaviors. Among these, biogenic amines – nitrogenous compounds that serve as essential neuromodulators in animals – have only recently been detected in floral nectar.
Marta Barberis +9 more
wiley +1 more source
Neuropeptide-induced hypothermia and the course of central nervous system disease mediated by temperature-sensitive mutants of vesicular stomatitis virus [PDF]
, 1985 Sharon C. Doll, Terry C. Johnson
openalex +1 more source
ChemistryOpen, EarlyView.Structure‐based virtual screening of PubChem compounds identifies two novel epalrestat and ranirestat‐like inhibitors with improved affinity and pharmacokinetic profiles targeting aldose reductase. Molecular docking, ADMET filtering, and 500‐ns molecular dynamics simulations confirm the stability and interaction specificity of the candidates ...
Mohd Shahnawaz Khan +3 more
wiley +1 more source
Modulation of immunity and hypersensitivity by sensory neuropeptides. [PDF]
, 1984 D G Payan, J D Levine, E J Goetzl
openalex +1 more source
Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates
PROTEOMICS, EarlyView.ABSTRACT Fluctuating salinity is symptomatic of climate change challenging aquatic species. The melting of polar ice, rising sea levels, coastal surface and groundwater salinization, and increased evaporation in arid habitats alter salinity worldwide. Moreover, the frequency and intensity of extreme weather events such as rainstorms and floods increase,
Maxime Leprêtre +3 more
wiley +1 more source
Neuropeptides and their evolution
Parasitology, 1996 SUMMARYNeuropeptides are ubiquitous signalling molecules in all metazoans possessing nervous systems, from the simple nerve nets of the cnidarians to the immensely complex systems of mammals. While the discipline of peptide neuroendocrinology was born through the study of higher vertebrates, there now exists a plethora of information regarding ...
openaire +3 more sources
PROTEOMICS, EarlyView.ABSTRACT Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and pathological protein aggregation. Comprehensive quantitative proteomics of brain tissues from AD patients is critical for pursuing a better understanding of the molecular mechanisms that drive AD progression.
Mehrdad Falamarzi Askarani +3 more
wiley +1 more source