Comorbidity Patterns Between Hearing Loss and Symptomatic Dizziness in Middle‐Aged and Older Adults
ABSTRACT Objective To explore the comorbidity patterns between hearing loss and symptomatic dizziness (HL‐SD) in middle‐aged and older adults. Methods This cross‐sectional study used data from the 1999 to 2004 National Health and Nutrition Examination Survey (NHANES). After excluding incomplete data, 2961 participants aged 40–69 were analyzed. Logistic
Chun‐Yan Liu +6 more
wiley +1 more source
Structural insights into the binding mode of the hypnotic drug vornorexant to orexin receptors
The crystal structure of the human orexin type 2 receptor–vornorexant complex (3.29 Å resolution) and orexin type 1 receptor docking revealed a conserved U‐shaped binding conformation, explaining the high affinity and balanced dual antagonism of this dual orexin receptor antagonist. The structural data validate the rational design that incorporated a 1,
Masashi Mima +4 more
wiley +1 more source
Peptidomic Identification of Behaviour-Modulating Putative Neuropeptides in <i>Schistosoma mansoni</i> Miracidia. [PDF]
Fogarty CE +7 more
europepmc +1 more source
This study tests whether early‐life maternal association buffers offspring from the effects of prenatal stress in a facultatively social lizard. Despite clear effects of maternal glucocorticoids on growth and social behaviour, social associations did not mitigate these effects, revealing limits to social buffering in this species.
Kirsty J. MacLeod +4 more
wiley +1 more source
Calcitonin‐like diuretic hormone influences reproduction in adult female Rhodnius prolixus
Highlights • CT/DH‐like immunoreactivity is present in female reproductive tissues • CT/DH receptor transcripts are expressed in the fat body and ovaries • RNAi knockdown of CT/DH receptors reduces egg number and hatching rate • Rhopr‐CT/DH increases RhoprVg1 and RhoprVgR expression in ovaries in vitro • Rhopr‐CT/DH stimulates oviduct contractions in a
Areej N. Al‐Dailami +2 more
wiley +1 more source
Global Profiling of Post-Translationally Modified Crustacean Neuropeptidome Trends Affiliated with Feeding Activity. [PDF]
Fields L +5 more
europepmc +1 more source
Adaptation of the invasive pest Drosophila suzukii to a specialized nutritional niche
Unlike most Drosophila larvae that feed on spoiled food, Drosophila suzukii larvae thrive on ripening fruits and consequently face a low‐protein, high‐carbohydrate nutritional challenge. Comparisons of growth among D. suzukii, D. biarmipes, and D. melanogaster larvae across diets with varying protein‐to‐carbohydrate ratios demonstrate that D.
Yan Hou, Ying Zhen
wiley +1 more source
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley +1 more source
Dense and distributed neuropeptide network in the nerve net of Hydra vulgaris. [PDF]
De La Cruz Rothenfusser J +3 more
europepmc +1 more source
Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu +5 more
wiley +1 more source

