Results 71 to 80 of about 65,188 (311)

Fluorescence Imaging with Single-Molecule Sensitivity and Fluorescence Correlation Spectroscopy of Cell-Penetrating Neuropeptides

, 2011
Neuropeptide plasma membrane interactions in the absence of a corresponding specific receptor may result in neuropeptide translocation into the cell.
Vladana Vukojević, Astrid Gräslund, Bakalkin, G, Vukojević, V, Gräslund, A, Gräslund, Astrid,, Vukojevic, Vladana, Bakalkin, Georgy, Georgy Bakalkin   +8 more
core   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source

Evolution and Comparative Physiology of Luqin-Type Neuropeptide Signaling

Frontiers in Neuroscience, 2020
Luqin is a neuropeptide that was discovered and named on account of its expression in left upper quadrant cells of the abdominal ganglion in the mollusc Aplysia californica.
Luis Alfonso Yañez-Guerra, Maurice R. Elphick   +1 more
doaj   +1 more source

Neuropeptides in platyhelminths

Parasitology, 1991
The neuropeptide story began in 1928 with the description by Ernst Scharrer of gland-like nerve cells in the hypothalamus of the minnow,Phoxinus laevis.Because these nerve cells were overwhelmingly specialized for secretory activity, overshadowing other neuronal properties, Scharrer termed them ‘neurosecretory neurons’.
Fairweather, Ian, Halton, D W
openaire   +2 more sources

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source

The neuroscience of cancer: Focus on neuropeptidergic systems

Acta Pharmaceutica Sinica B
Tumors are complex, highly heterogeneous diseases that place an enormous burden on the world's healthcare systems. Updating understanding of tumor initiation and progression is critical and the current breakthrough lies in cancer neuroscience, which ...
Zikai Dong, Yongfei Wang, Weilin Jin
doaj   +1 more source

Neuropeptides in the Gonads: From Evolution to Pharmacology

Frontiers in Pharmacology, 2010
Vertebrate gonads are the sites of synthesis and binding of many peptides that were initially classified as neuropeptides. These gonadal neuropeptide systems are neither well understood in isolation, nor in their interactions with other neuropeptide ...
Nicolette L McGuire, George E Bentley, George E Bentley   +2 more
doaj   +1 more source

Structure and function of sea urchin neuropeptides

, 2010
PhDThe subject of this thesis is the identification and functional characterization of sea urchin neuropeptides. Neuropeptides are important mediators of neural signalling in all known animals with a nervous system, including bilaterians, ctenophorans ...
Rowe, Matthew Lyndon
core  

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Lower Striatal and Cortical Calretinin Interneuron Density Associated With Altered Social Behavior in Cntnap2 Knockout Mice

Autism Research, EarlyView.
ABSTRACT Variants in the CNTNAP2 gene, encoding the cell adhesion molecule CASPR2, have been identified as genetic risk factors for autism spectrum disorder (ASD). However, the mechanisms through which CNTNAP2 dysfunction alters circuit function remain unknown.
Krisztina Sáfár, Vivien Szendi, Paulina Hoppa, Yutong Wang, Fanni Á. Seres, Szilvia Bartók, Tyler Teadora, Lei Shi, Árpád Dobolyi, Gina Puska, István Adorján   +10 more
wiley   +1 more source