Results 131 to 140 of about 200,218 (362)
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman+4 more
wiley +1 more source
Quantum Mechanics and the Cookie Cutter Paradigm [PDF]
What has so far prevented us from decrypting quantum mechanics is the Cookie Cutter Paradigm, according to which the world's synchronic multiplicity derives from surfaces that carve up space in the manner of three-dimensional cookie cutters. This insidious notion is shown to be rooted in our neurophysiological make-up. An effort is made to liberate the
arxiv
Objective Vascular NOTCH3 protein ectodomain aggregation is a pathological hallmark of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a monogenic small vessel disease typically caused by cysteine‐altering variants in NOTCH3.
Minne N. Cerfontaine+10 more
wiley +1 more source
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by selective degeneration of upper and lower motor neurons. Leucine‐rich repeats and sterility α mutations in motif 1 (LRSAM1) has been proven to be involved in the pathogenesis of ALS.
Ji‐Yao Qin+6 more
wiley +1 more source
Géométrie et cognition; l'exemple du continu [PDF]
In this paper I propose the idea to establish a clear distinction between the foundations of truth and the foundations of meaning in Mathematics. I explore on the most basic example, the mathematical line, the possibility that the foundations of its meaning are provided by a protomathematical object resulting from the identification by our perceptual ...
arxiv
Objective To compare clinical and radiological outcomes among relapsing multiple sclerosis patients treated with autologous hematopoietic stem cell transplantation (AHSCT), alemtuzumab (ATZ), and ocrelizumab (OCR). Methods From a London (UK) hospital‐based observational cohort, modeled data were obtained from 621 relapsing–remitting multiple sclerosis ...
Paolo Antonio Muraro+16 more
wiley +1 more source
Polarization Theory of Motivations, Emotions and Attention [PDF]
A new theory of motivations, emotions and attention is suggested, considering them as functions of sensory systems. The theory connects neurophysiological mechanisms of mental phenomena with the change of metabolic and functional state of perceptive neurons, which is reflected in the degree of polarization of a cell membrane.
arxiv