Experimental Physiology, EarlyView.Abstract Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage‐gated calcium and potassium channels by G protein‐coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α‐conotoxin Vc1.1 activate GABAB receptors (GABABR), resulting in inhibition of CaV2.2 and ...
Mariana Brizuela +4 more
wiley +1 more source
Exploring Salivary Brain-Derived Neurotrophic Factor (BDNF) as a Potential Biomarker of Neuroplasticity in Older Adults Through Exergaming. [PDF]
CureusPistritto SC +5 more
europepmc +1 more source
Early adversity and the comorbidity between metabolic disease and psychopathology
The Journal of Physiology, EarlyView.Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas +1 more
wiley +1 more source
Ultrastructure of astrocytes using volume electron microscopy: A scoping review
The Journal of Physiology, EarlyView.Abstract figure legend A complete overview on astrocyte ultrastructure with volume electron microscopy. The morphology of astrocytes under physiological and pathological conditions plays a role in brain homeostasis, synaptic activity and structural support, but their morphological complexity and heterogeneity are still poorly quantified.
Vanessa Chiappini +7 more
wiley +1 more source
Considering the Effects of Cannabinoids and Exercise on the Brain: A Narrative Review. [PDF]
Sports (Basel)Rajaei AY +4 more
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend This study aimed to determine whether early sensorimotor restriction (SMR) alters mitochondrial enzyme activities in rat muscles and brain structures. SMR was induced via immobilizing the hind limbs of pups for 16 h per day during the dark phase from birth to postnatal day (PND) 28.
Mélanie Van Gaever +4 more
wiley +1 more source
Correction: Dual-target tDCS and dual-task training modulate neuroinflammation and neuroplasticity: transcriptomic and behavioral evidence in stroke rehabilitation. [PDF]
Front Rehabil SciFu Y +6 more
europepmc +1 more source
Acute intermittent hypercapnic hypoxia augments left ventricular contractility
The Journal of Physiology, EarlyView.Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall +8 more
wiley +1 more source
Combining nonlinear mechanical stimulation via a chaotic mathematical model and game-based exercise for upper extremity rehabilitation in children with spastic hemiparetic cerebral palsy: a pilot study. [PDF]
Biomed Eng OnlineHosseini P +10 more
europepmc +1 more source