Results 101 to 110 of about 93,816 (307)
Frontiers in Aging Neuroscience, 2021 Clinical and basic research suggests that exercise is a safe behavioral intervention and is effective for improving cognitive function in cerebrovascular diseases, including subcortical ischemic vascular dementia (SIVD).
Ryo Ohtomo +16 more
doaj +1 more source
Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: Implication for neuroprotective therapies [PDF]
, 2013 Neuroprotective therapies based on brain-derived neurotrophic factor (BDNF) administration have been proposed for Huntington's disease (HD) treatment. However, our group has recently reported reduced levels of TrkB in HD mouse models and HD human brain ...
Alberch, J. +5 more
core +1 more source
Post-ischaemic immunological response in the brain: targeting microglia in ischaemic stroke therapy [PDF]
, 2020 Microglia, the major endogenous immune cells of the central nervous system, mediate critical degenerative and regenerative responses in ischaemic stroke.
Chen, Ruoli +4 more
core +3 more sources
Advanced Science, EarlyView.This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song +15 more
wiley +1 more source
Sex differences in the role of AKAP12 in behavioral function of middle-aged mice
Biology of Sex DifferencesA-kinase anchoring protein 12 (AKAP12) is a key scaffolding protein that regulates cellular signaling by anchoring protein kinase A (PKA) and other signaling molecules.
Hidehiro Ishikawa +13 more
doaj +1 more source
Frontiers in Neurology, 2019 Close-head concussive injury, as one of the most common forms of traumatic brain injury (TBI), has been shown to induce cognitive deficits that are long lasting.
Ying Deng-Bryant +8 more
doaj +1 more source
Requirement for preclinical prioritization of neuroprotective strategies in stroke: Incorporation of preconditioning [PDF]
Conditioning Medicine, 2018, 2019 Acute neuroprotection in numerous human clinical trials has been an abject failure. Major systemic-and procedural-based issues have subsequently been identified in both clinical trials and preclinical animal model experimentation. As well, issues related to the neuroprotective moiety itself have contributed to clinical trial failures, including late ...
arxiv
Preliminary Report: Cerebral blood flow mediates the relationship between progesterone and perceived stress symptoms among female club athletes after mild traumatic brain injury [PDF]
arXiv, 2020 Female athletes are severely understudied in the field of concussion research, despite higher prevalence for injuries and tendency to have longer recovery time. Hormonal fluctuations due to normal menstrual cycle (MC) or hormonal contraceptive (HC) use have been shown to impact both post-injury symptoms and neuroimaging measures, but have not been ...
arxiv
Perinatal neuroprotection [PDF]
F1000Prime Reports, 2014 Fetal or neonatal brain injury can result in lifelong neurologic disability. The most significant risk factor for perinatal brain injury is prematurity; however, in absolute numbers, full-term infants represent the majority of affected children.
Salmeen, Kirsten E. +2 more
openaire +2 more sources
Advanced Science, EarlyView.A wireless‐charging sustained oxygen release from conductive microgels (SOCO) served as an antenna and an on‐demand O2 release for nerve regeneration is developed. Introducing “electromagnetic messenger”, using external alternating magnetic field (AMF) to enhance catalytic oxygen release and electrical stimulation to promote the reconstruction of blood
Hoi Man Iao +15 more
wiley +1 more source