Results 101 to 110 of about 184,954 (326)

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

Neuroprotection
Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal, Saurabh Singhal, Bernhard T. Baune   +2 more
doaj   +1 more source

Neuroprotection, Recovery of Function and Endogenous Neurogenesis in Traumatic Spinal Cord Injury Following Transplantation of Activated Adipose Tissue [PDF]

, 2019
Stephana Carelli, Toniella Giallongo, Federica Rey, Mattia Colli, Delfina Tosi, Gaetano Bulfamante, Anna Maria Di Giulio, Alfredo Gorio   +7 more
openalex   +1 more source

Neuroprotective effects of carnitinoid compounds in rodent cellular and in vivo models of mitochondrial complex I dysfunction [PDF]

, 2019
Rotenone-mediated mitochondrial complex I inhibition was used to model Parkinson’s disease-like syndrome in Lewis rats. Tyrosine hydroxylase immunolabeling demonstrated a decrease in the number of dopaminergic neurons as well as aberrant morphology in ...
Steliou, Kosta
core  

Microglial Membranes Wrapped Ultrasmall Medium‐Entropy Ru Single‐Atom Nanozyme: Enhanced Catalysis for Accelerating Inflammation/Redox Microenvironment Regulation in Intracerebral Hemorrhage

Advanced Science, EarlyView.
PtRhIr/Ru SAN@M nanozymes cross the blood–brain barrier and selectively accumulate in hemorrhagic brain regions. By mimicking multiple enzyme activities, they attenuate oxidative stress, modulate microglial polarization toward an anti‐inflammatory phenotype, inhibit ferroptosis, and promote neuronal repair.
Jiebo Li, Penghui Wei, Yuanbo Pan, Hongjia Zheng, Jiajun Hu, Qianxi Chen, Zhongyuan Shen, Yongrui Hu, Jiajun Wu, Fuxin Lin, Fuxiang Chen, Chenyu Ding, Wenhua Fang, Yuanxiang Lin, Dezhi Kang, Yuxiang Gu, Yang Zhu, Dengliang Wang   +17 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

The effects and mechanisms of stem cells and exosomes on neurological function protection and recovery after ischemic stroke

Neuroprotection
Stroke can cause motor sensory impairment and cognitive impairment. Current interventions focus on thrombolysis or thrombectomy in the acute stage, and promoting the recovery of neurological function during the chronic stage.
Weihong Du, Yuxian He, Liangchen Li, Xinchun Jin, Panpan Geng   +4 more
doaj   +1 more source

Therapeutic potential of stem cells in pediatric neurology: Insights from clinical trials

Neuroprotection
Pediatric neurological disorders comprise diverse conditions that impair nervous system function in children and contribute substantially to global disease burden.
Daniel Bou Najm, Saada Alame
doaj   +1 more source

Neuroprotection in Ischemia–Reperfusion Injury: An Antiinflammatory Approach Using a Novel Broad-Spectrum Chemokine Inhibitor [PDF]

, 2001
John S. Beech, Jill Reckless, David E. Mosedale, David J. Grainger, Steven Williams, David Menon   +5 more
openalex   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Biological relationship between Parkinson's disease and gallstone disease

Neuroprotection
Compelling evidence indicates a significant connection between dysfunction of the gastrointestinal tract, the gut microbiome, and Parkinson's disease (PD), which aligns with the notion of the “gut–brain axis”.
Chao Jiang, Jingying Ma, Jingyu Mu, Yuanyuan Fu, Yan Zhao, Yiming You, Zhiqiang Cui, Chuang Guo   +7 more
doaj   +1 more source