Results 271 to 280 of about 174,618 (333)
Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury
Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li+5 more
wiley +1 more source
Lithium and neuroprotection: a review of molecular targets and biological effects at subtherapeutic concentrations in preclinical models of Alzheimer's disease. [PDF]
De-Paula VJR, Radanovic M, Forlenza OV.
europepmc +1 more source
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou+8 more
wiley +1 more source
Voluntary running partially prevents photoreceptor cell death in retinitis pigmentosa. [PDF]
Agadagba SK+4 more
europepmc +1 more source
Stroke is a leading cause of death and disability worldwide, often due the inadequate restoration of cerebral blood flow following vascular recanalization. Our study demonstrates that a simple technique called RLIPC (remote limb ischemic preconditioning), which involves briefly restricting blood flow in a limb, protects the brain during a stroke by ...
Chaoran Dou+8 more
wiley +1 more source
hUMSC-Exosomes suppress TREM1-p38 MAPK signaling via HMGB1-dependent mechanisms to reprogram microglial function and promote neuroprotection in ischemic stroke. [PDF]
Zhang Z+6 more
europepmc +1 more source
ABSTRACT Background Preterm birth is a priority area for practice improvement internationally. Clinical practice guidelines improve the efficiency of clinical decision‐making and, when implemented effectively, may advance the quality and consistency of care. Guideline implementation tools may help to further optimise the use of guidelines.
Briar Hunter+6 more
wiley +1 more source