Results 271 to 280 of about 129,703 (302)

Calycosin Targets the CYP1B1‐AKT/SP1‐GPX4 Axis to Modulate Ferroptosis in Colorectal Carcinogenesis

Phytotherapy Research, EarlyView.
Mechanism of Calycosin in Regulating Ferroptosis in Colorectal Cancer via Binding to CYP1B1. ABSTRACT Calycosin, a natural flavonoid small‐molecule compound derived from traditional Chinese medicine, has demonstrated remarkable pharmacological activity in the field of cancer therapy.
Lihan Bie, Xin Lei, Di Wu, Yang Zhang, Chengshan He, Luyao Liu, Jiawei Zhou, Xin Zhou, Yingying Lu, Zheng Xu   +9 more
wiley   +1 more source

Novel PPAR-γ agonists as potential neuroprotective agents against Alzheimer's disease: rational design, synthesis, in silico evaluation, PPAR-γ binding assay and transactivation and expression studies. [PDF]

RSC Adv
D P, Hani U, Haider N, Talath S, Shanmugarajan D, P P, P A, Prashantha Kumar BR.   +7 more
europepmc   +1 more source

Enhanced Active Packaging Properties Through the Incorporation of Pomegranate Seed Oil Micro‐ and Nanoparticles

Packaging Technology and Science, EarlyView.
Biodegradable cassava starch films were developed incorporating micro‐ and nanoencapsulated pomegranate seed oil (PSO). The films exhibited enhanced mechanical flexibility, antioxidant activity and UV‐barrier properties. Particle size influenced the functional behaviour, highlighting lipid encapsulation as a key strategy to stabilize bioactive ...
Amanda Tibães Lopes, Maria Nunes Medeiros, Isadora Cachuit Cardoso Mota, Sandra de Oliveira Silva, Ana Paula Rodrigues, Gustavo Molina, Guilherme Carneiro, Franciele Maria Pelissari   +7 more
wiley   +1 more source

Multi‐Functional S‐HA/ASTA NPs Coating on Biodegradable ZE21B Alloy for Cerebrovascular Applications

Rare Metals, EarlyView.
ABSTRACT Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cerebrovascular implants due to their good mechanical properties and biosafety. However, rapid degradation and delayed endothelialization pose challenges. To address these issues, this study introduces a multifunctional composite coating.
Aqeela Yasin, Mujahid Iqbal, Yachen Hou, Jingan Li, Shaokang Guan   +4 more
wiley   +1 more source

Neuroprotective agents, Natural Plant Herbs & Drugs in Ischemic Stroke: A Review

, 2017
Noman Ahmad, Zafar U. Khan, Noorul Hasan, Abdul W. Basit   +3 more
openalex   +1 more source

New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics

Rare Metals, EarlyView.
ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu, Shao‐Sheng Jia, Rong‐Bang Sun, Tong Zhang, Ling‐Chuang Bai, Di Mei, Shi‐Jie Zhu, Lan Chen, Shao‐Kang Guan   +8 more
wiley   +1 more source

A Multifunctional Bioactive Nanoscale Coating Deposited by Atmospheric Pressure Plasma Polymerization of Peppermint Essential Oil

Small, EarlyView.
Atmospheric plasma polymerization transforms peppermint essential oil into ultrathin, substrate‐independent bioactive coatings with antioxidant, contact‐active antibacterial, and immunomodulatory functions. The coating disrupts Gram‐negative pathogens, potentiates prophylactic antibiotics, suppresses pro‐inflammatory signaling, and promotes M2 ...
Trong Quan Luu, Xuan Duy Do, Tuyet Pham, Ngoc Huu Nguyen, Richard Bright, Wenshao Li, Xiangyang Guo, Vi Khanh Truong, Andrew Hayles, Krasimir Vasilev   +9 more
wiley   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

Integrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source

Formulation and characterization of nanoparticles loaded with curcumin and amantadine as a promising neuroprotective agent

Anne F. Alex, Ayalur Kodakara Kochugovindan Unni, Gayathri Kumararaja   +2 more
openalex   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source