Baseline Results Investigate APOE‐Memory Connection in Latin‐American Population at Risk for Dementia ‐ LatAm‐FINGERS Initial Insights [PDF]
Abstract Background Latin America (LA) faces heightened vulnerability to modifiable dementia risk factors. Early identification of at‐risk individuals is crucial for implementing effective preventive strategies. The Free and Cued Selective Reminding Test with Immediate Recall (FCSRT‐IR) is promising in early detection of mnemonic impairment, with high ...
Friedlaender C +45 more
europepmc +2 more sources
The relationship between amyloid‐b and cognition in young‐onset Mild Cognitive Impairment: the influence of disease duration [PDF]
Abstract Background The effect of amyloid‐b brain deposition on cognition is still debated, since it has been shown that its accumulation begins almost 15 years before cognitive symptoms' onset, then reaches a plateau while cognition continues to decline. We studied if there is a parallel between amyloid‐b deposition and cognitive performances in young‐
Carbone C +12 more
europepmc +2 more sources
Markers of atrophy progression in patients with young‐onset cognitive complaints not due to Alzheimer’s Disease [PDF]
Abstract Background In clinical settings, the prognosis of patients with subtle cognitive complaints and no imaging evidence of neurodegeneration is often challenging, especially in conditions unrelated to Alzheimer’s Disease (AD). We aimed to identify which baseline indicators can help in the clinical decision‐making process of patients with ...
Carbone C +12 more
europepmc +2 more sources
Exploring Social Networks in the LatAmFINGERS Trial: The Importance of Pre‐Intervention Social Involvement [PDF]
Abstract Background LatAm‐FINGERS is a non‐pharmacological multicenter randomized clinical trial aimed at preventing cognitive impairment. The intervention advocates for a lifestyle change based on diet, exercise, risk factor control, cognitive training, and socialization.
Cristalli C +22 more
europepmc +2 more sources
Inclusive Clinical Trials in Alzheimer’s Disease: A Latin American Perspective from LatAm FINGERS [PDF]
Abstract Background The LatAm‐FINGERS trial marks a pioneering initiative as the first non‐pharmacological clinical trial encompassing participants from 12 Latin American countries, including Argentina, Brazil, Bolivia, Chile, Colombia, Costa Rica, Ecuador, Dominican Republic, Mexico, Peru, Puerto Rico, and Uruguay.
Crivelli L +23 more
europepmc +2 more sources
LatAm‐FINGERS: Navigating Diversity in the Engagement of a Subcontinental Trial for Dementia Prevention [PDF]
Abstract Background LatAm‐FINGERS is the first non‐pharmacological multicenter randomized clinical trial aimed at preventing cognitive impairment in Latin America. It encompasses twelve countries that collectively represent 45% of the territory in the Americas.
Calandri I +22 more
europepmc +2 more sources
Frequency, entity and determinants of fatigue in Charcot–Marie–Tooth disease
Abstract Background and purpose Fatigue, a disabling symptom in many neuromuscular disorders, has been reported also in Charcot–Marie–Tooth disease (CMT). The presence of fatigue and its correlations in CMT was investigated. Methods The Modified Fatigue Impact Scale (MFIS) was administered to CMT patients from the Italian Registry and a control group ...
Marta Bellofatto +26 more
wiley +1 more source
O teste da Torre de Londres: comparação entre a versão tradicional e a aplicação computadorizada
Introdução: A Torre de Londres (Tower of London – ToL) é uma tarefa neuropsicológica desenvolvida para avaliação da capacidade cognitiva de planejamento.
Adriana Borges +6 more
doaj +1 more source
El uso del estudio de casos en la investigación en psicoterapia
Este trabajo revisa el estado actual de la investigación mediante Estudio de Casos (EC) en psicoterapia. El uso de esta metodología se remonta a los comienzos de la disciplina y es hoy una forma de investigación utilizada ampliamente.
Mariano G. Scandar
doaj +1 more source
Neuropsicologia Clínica: Notas Históricas, Fundamentos Teórico-Metodológicos e Diretrizes para Formação Profissional [PDF]
Resumo A Neuropsicologia se concentra em disciplinas oriundas da interface entre a neurociência e a psicologia cognitiva, e sua pesquisa converge da relação entre o cérebro e o comportamento.
José Roberto Wajman
doaj +1 more source

