Results 121 to 130 of about 358,966 (235)

A call for ethical, equitable, and effective artificial intelligence to improve care for all people with epilepsy: A roadmap. A report by the ILAE Global Advocacy Council and Big Data Commission

open access: yesEpilepsia, EarlyView.
Abstract The artificial intelligence (AI) revolution is upon us. It will inevitably form a central component of epilepsy workflows and patient advocacy. Therefore, it behooves us as health care providers to ride the crest of this wave and guide its direction for the benefit of all people with epilepsy.
Colin B. Josephson   +13 more
wiley   +1 more source

Towards a Latin American neuropsychiatry: challenges and opportunities. [PDF]

open access: yesLancet Reg Health Am
Ramírez Bermúdez J   +11 more
europepmc   +1 more source

Altered neurostructural development in magnetic resonance imaging‐negative pediatric epilepsy: A large‐scale multicenter study of 1919 children

open access: yesEpilepsia, EarlyView.
Abstract Objective Addressing the poorly understood impact of pediatric epilepsy on neurodevelopment, this large‐scale study delineates age‐ and sex‐stratified neurostructural trajectories in magnetic resonance imaging (MRI)‐negative pediatric epilepsy to identify periods of maximal developmental divergence from healthy controls.
Yingfan Wang   +10 more
wiley   +1 more source

Baseline characteristics and feasibility of clinical outcome measures in CDKL5 deficiency disorder: The CANDID observational study

open access: yesEpilepsia, EarlyView.
Abstract Objective CDKL5 deficiency disorder (CDD) is a rare X‐linked developmental and epileptic encephalopathy caused by loss‐of‐function variants in the CDKL5 gene. Preclinical experiments using enzyme replacement or gene therapies show promise and could be transformative therapies.
Xavier Liogier d'Ardhuy   +8 more
wiley   +1 more source

Predictive value of seizure onset for gross motor dysfunction in individuals with pathogenic GABRB2 and GABRB3 variants

open access: yesEpilepsia, EarlyView.
Abstract Objective Pathogenic variants in γ‐aminobutyric acid type A (GABAA) receptor genes have been associated with a wide spectrum of neurological disorders. We aimed to delineate the clinical trajectories associated with gain‐of‐function (GoF) and loss‐of‐function (LoF) variants in GABRB2 and GABRB3, and to develop a risk‐prediction model for gross
Sebastian Ortiz   +73 more
wiley   +1 more source

Unstable slow oscillations couple with epileptogenic fast‐rhythm bistability in sleep‐related epilepsy: A stereoelectroencephalographic study

open access: yesEpilepsia, EarlyView.
We examined the functional relationship between large‐scale δ‐band phase synchrony and local epileptogenic β–γ‐band amplitude bistability during NREM sleep. Increased synchrony and strong bistability characterized the epileptogenic zone, with strongest effects during N2 sleep, when seizures most frequently occur.
Gaia Burlando   +14 more
wiley   +1 more source

Poststroke epilepsy is associated with vascular cognitive disorder in young stroke patients: The ODYSSEY study

open access: yesEpilepsia, EarlyView.
Abstract Objective Cognitive disorder is common after stroke at a young age, especially in patients with poststroke epilepsy (PSE). Whether the causative mechanism is direct (due to epilepsy‐related network alterations) or indirect (due to effect‐modifiers such as stroke severity) is not fully understood.
Frederik J. Reitsma   +26 more
wiley   +1 more source

A Data-Driven Psychiatric Disorder Subtype Defined by Significant Enlarged Ventricles and Cognitive Impairment: A Replication Study. [PDF]

open access: yesNeuropsychopharmacol Rep
Onitsuka T   +17 more
europepmc   +1 more source

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