Results 121 to 130 of about 356,437 (285)

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama   +16 more
wiley   +1 more source

Editorial: Catatonia across the lifespan

open access: yesFrontiers in Psychiatry, 2022
Jorge Cuevas-Esteban   +6 more
doaj   +1 more source

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: the Randomized, Phase 3, TULIP‐SC Study

open access: yesArthritis &Rheumatology, Accepted Article.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate‐to‐severe SLE activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly for 52 weeks (1:1 ...
Susan Manzi   +12 more
wiley   +1 more source

Neurobehavioral Assessment of Sensorimotor Function in Autism Using Smartphone Technology

open access: yesAutism Research, EarlyView.
ABSTRACT Differences in sensorimotor processing represent an important, yet underrecognized, feature of autism; typically assessed through subjective observations, which, although important, are susceptible to biases. To complement these observations, a more objective approach to assess sensorimotor function may be possible through reflex‐based ...
Kayleigh D. Gultig   +19 more
wiley   +1 more source

Neuropsychiatry

open access: yesPsychiatric Clinics of North America, 2020
Vassilis E. Koliatsos   +2 more
openaire   +2 more sources

Parental Stress and Caregiver Role Modulate Child–Caregiver Prosodic Synchrony in Autism: A Computational Analysis

open access: yesAutism Research, EarlyView.
ABSTRACT Parental stress influences parent–child interactions in typical development and is a prognostic factor of autism outcome. However, we still do not know to what extent parental stress affects parent–child interactions and whether caregiver role matters.
Maria Grazia Logrieco   +11 more
wiley   +1 more source

Pharmacokinetic profiles of sertraline in pregnancy as a predictor of postpartum depressive symptoms

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To characterize pharmacokinetic changes of sertraline and its metabolite during pregnancy and postpartum, and their relationship to maternal postpartum depressive symptoms. Methods This was a prospective observational, longitudinal study of pregnant women with a major depressive disorder treated with sertraline (N = 185 women, 205 pregnancies ...
Sílvia M. Illamola   +8 more
wiley   +1 more source

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