Results 121 to 130 of about 399,854 (379)

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

open access: yesAdvanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng   +40 more
wiley   +1 more source

Spatiotemporal Characterization of the Functional MRI Latency Structure with Respect to Neural Signaling and Brain Hierarchy

open access: yesAdvanced Science, EarlyView.
Resting‐state fMRI captures intrinsic brain activity, yet the physical significance of latency structures remains unclear. In this study, the spatiotemporal properties of fMRI‐derived latency structures are examined by linking them to biophysical model‐based neural functions, intrinsic neural timescales, and functional gradients.
Hyoungshin Choi   +5 more
wiley   +1 more source

Case series: Potential use of guanfacine for safer management of behavioral disturbances in patients with dementia

open access: yesPCN Reports
Background Behavioral and psychological symptoms of dementia (BPSD), including irritability, agitation, and anxiety, are common and cause significant distress for both patients and caregivers.
Jeong Hoo Lee, Joji Suzuki
doaj   +1 more source

Repetitive transcranial magnetic stimulation in psychiatry

open access: yesAnnals of Indian Academy of Neurology, 2011
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive and relatively painless tool that has been used to study various cognitive functions as well as to understand the brain-behavior relationship in normal individuals as well as in those ...
Biswa Ranjan Mishra   +5 more
doaj   +1 more source

Incidence and correlates of delirium in a West African mental health clinic [PDF]

open access: yes, 2010
Objective: <br/> <br/> To determine the incidence of delirium in those patients presenting to a psychiatric clinic in Nigeria and to examine if any demographic or clinical variables were correlated with this diagnosis. <br/> <br/
Abiodun   +45 more
core   +1 more source

Neuropsychiatry [PDF]

open access: yesClinical Medicine, 2002
Simon, Fleminger, Mike, Dilley
openaire   +2 more sources

EETs Reduction Contributes to Granulosa Cell Senescence and Endometriosis‐Associated Infertility via the PI3K/AKT/mTOR Signaling Pathway

open access: yesAdvanced Science, EarlyView.
1) 14, 15‐EET levels were decreased in ovarian granulosa cells, follicular fluid, peritoneal fluid from endometriosis patients. 2) EETs reduction in endometriosis follicular fluid aggravated granulosa cell senescence. 3) ROS reduced 14, 15‐EET levels by upregulating EPHX2 through a mechanism involving histone methylation modification.
Xiang Lin   +11 more
wiley   +1 more source

First episode of psychiatric and neuropsychiatric disease among patients infected with COVID‐19: A scoping review

open access: yesPCN Reports
This scoping review aims to examine the frequency and prevalence of neuropsychiatric disorders reported in patients infected with coronavirus disease 2019, and the mechanisms by which these develop during and post infection.
Wali Yousufzai   +12 more
doaj   +1 more source

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