Results 131 to 140 of about 358,966 (235)

Women with epilepsy: Evidence‐based counseling across the lifespan

open access: yesEpilepsia, EarlyView.
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn   +7 more
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

open access: yesEpilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Isolated absence epilepsy associated with a de novo FBXW7 missense variant in the F‐box domain

open access: yesEpilepsia Open, EarlyView.
Abstract The FBXW7 gene encodes a substrate‐recognition component of the Skp1‐Cul1‐F‐box (SCF) E3 ubiquitin ligase complex, which targets key regulatory proteins for proteasomal degradation. Recently, loss‐of‐function FBXW7 variants have been associated with a novel neurodevelopmental disorder characterized by heterogeneous clinical features.
Anees Muhammad   +10 more
wiley   +1 more source

Structural brain imaging biomarkers for predicting seizure recurrence after a first unprovoked seizure

open access: yesEpilepsia Open, EarlyView.
Abstract Objectives Predicting seizure recurrence following a first unprovoked seizure (FUS) remains a significant clinical challenge, especially when routine clinical magnetic resonance imaging (MRI) and EEG do not reveal abnormalities diagnostic of epilepsy.
Suyi Ooi   +7 more
wiley   +1 more source

Trajectories of quality of life, anxiety and depressive symptomatology, and health‐related work productivity after first seizure events

open access: yesEpilepsia Open, EarlyView.
Abstract Objective First seizure events are common and may exert an immediate and profound impact on people's lives. Less understood are their long‐term consequences. This prospective, longitudinal study aimed to measure and compare psychosocial and health‐related work productivity trajectories following first seizure events of various etiologies ...
Emma Foster   +13 more
wiley   +1 more source

Determinants Of Cognitive Impairment Among Older Adults In Hanoi, Vietnam: Insights From The Montreal Cognitive Assessment. [PDF]

open access: yesClin Neuropsychiatry
Hue DT   +10 more
europepmc   +1 more source

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