Results 81 to 90 of about 43,555 (263)

Hyperpolarization of [1‐13C]Ketoisocaproate‐d2 by Reversible Exchange with Parahydrogen Enables Profiling of Branched‐Chain‐Amino‐Acid Metabolism in Cellulo and in Vivo

Advanced Science, EarlyView.
We report the fast generation of biocompatible solutions of highly 13C‐hyperpolarized (≈11%) partially‐deuterated ketoisocaproate within <6 min using spin‐lock‐induced crossing and reversible exchange with parahydrogen (SLIC‐SABRE). This enables rapid detection of branched‐chain‐amino‐acid transferase 1 (BCAT1) protein expression and investigation of ...
Stefan Petersen, Philipp R. Groß, Paul M. Schmidt, Henri de Maissin, Asitan Rittinger, Robert Willing, Adriana Sacristán‐Martín, Lisa Heß, Jule Koch, Sebastian Lucas, Maxim Zaitsev, Dominik von Elverfeldt, Martin Grashei, Franz Schilling, Jan‐Bernd Hövener, André F. Martins, Max von Delius, Thomas Reinheckel, Andreas B. Schmidt   +18 more
wiley   +1 more source

NEURORADIOLOGY METHODS IN BRAIN TUMOR DIAGNOSIS [PDF]

, 2019
ilj rada je opisati i istaknuti važnost neuroradiologije u dijagnostici tumora mozga Tumori mozga zauzimaju svega 2% od sveukupnih tumora kod odraslih, nešto je češći kod djece oko 20%.
Milatić-Pantović, Lea
core  

Bayesian model selection for pathological neuroimaging data applied to white matter lesion segmentation. [PDF]

, 2015
In neuroimaging studies, pathologies can present themselves as abnormal intensity patterns. Thus, solutions for detecting abnormal intensities are currently under investigation.
Willem H. Bouvy, Sudre, Carole H., Bouvy, W, Josephine Barnes, Biessels, G, Biessels, Geert Jan, Barnes, Josephine, Sudre, C, Ourselin, Sebastien, Bouvy, Willem H., Sebastien Ourselin, Cardoso, MJ, Ourselin, S, M. Jorge Cardoso, Geert Jan Biessels, Cardoso, M. Jorge, Barnes, J, Sudre, Carole H.; id_orcid, Cardoso, M. Jorge; id_orcid, Carole H. Sudre   +19 more
core   +1 more source

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

Advanced Science, EarlyView.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo, Qiwen Yuan, Pengfei Zhang, Lin Sang, Zhong Zheng, Baotian Zhao, Xiu Wang, Chao Zhang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Ruijin Yang, Kai Zhang   +12 more
wiley   +1 more source

Effects of gadolinium contrast agent administration on automatic brain tissue classification of patients with multiple sclerosis [PDF]

, 2014
BACKGROUND AND PURPOSE: The administration of gadolinium contrast agent is a common part of MR imaging examinations in patients with MS. The presence of gadolinium may affect the outcome of automated tissue classification.
Tisell, Anders,, Warntjes, J B M, Lundberg, Peter,, Landtblom, Anne-Marie,, Lundberg, P,, Warntjes, Marcel Jan Bertus,, Tisell, A   +6 more
core   +1 more source

Flow-Diverting Stents During Mechanical Thrombectomy for Carotid Artery Dissection-Related Stroke: Analysis from a Multicentre Cohort

Brain Sciences
Background and Purpose: Mechanical thrombectomy in the context of internal carotid artery dissection (ICA-D) lesions is an undesirable procedure that may necessitate carotid stenting.
Osama Elshafei, Jonathan Cortese, Nidhal Ben Achour, Eimad Shotar, Jildaz Caroff, Léon Ikka, Cristian Mihalea, Vanessa Chalumeau, Maria Fernanda Rodriguez Erazu, Mariana Sarov, Nicolas Legris, Jean-Christophe Gentric, Frederic Clarençon, Laurent Spelle   +13 more
doaj   +1 more source

Clinical, Behavioral and Neuroradiological Phenotype in an Italian Cohort of Patients With Xia Gibbs Syndrome: A Multicenter Cross‐Sectional Study and Systematic Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous variants in the AHDC1 gene are associated with Xia Gibbs Syndrome (XGS), a genetic disorder with a highly variable phenotype. Cognitive impairment, motor delay, language delay, neonatal hypotonia, and sleep apnea are considered “cardinal” signs of the disease.
Giulia Cinelli, Stefania Della Vecchia, Patrizia Bergonzini, Elisa Caramaschi, Elisabetta Spezia, Claudia Parenti, Simona Filomena Madeo, Laura Lucaccioni, Cavalleri Francesca, Marisa Pugliese, Federico Raviglione, Clara Colonna, Olga Calabrese, Ilaria Stanghellini, Maria Carmen Marongiu, Enrico Biagioni, Anna Rita Ferrari, Roberta Battini, Lorenzo Iughetti   +18 more
wiley   +1 more source

Radiation Necrosis in Pediatric Patients with Brain Tumors Treated with Proton Radiotherapy [PDF]

, 2015
Background and purpose: Proton radiotherapy has been increasingly utilized to treat pediatric brain tumors, however, limited information exists regarding radiation necrosis among these patients.
Kralik, S.F., Ho, C.Y., Haskins, C.P., Finke, W., Buchsbaum, J.C., Shih, C.-S.   +5 more
core   +1 more source

Distribution of Cortical Diffusion Tensor Imaging Changes in Multiple Sclerosis

Frontiers in Physiology, 2020
PurposeDiffuse cortical damage in relapsing–remitting multiple sclerosis (RRMS) is clinically relevant but cannot be directly assessed with conventional MRI.
Benjamin Stock, Benjamin Stock, Benjamin Stock, Manoj Shrestha, Alexander Seiler, Alexander Seiler, Christian Foerch, Elke Hattingen, Helmuth Steinmetz, Ralf Deichmann, Marlies Wagner, René-Maxime Gracien, René-Maxime Gracien   +12 more
doaj   +1 more source

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness, Ameya S. Walimbe, Emily R. Strouphauer, Michio Hirano, Alejandro D. Iglesias, Valentina Emmanuele, Caitlin C. Griffin, Sheldon L. Kaplan, William A. Gomes, Karen K. Moeller, Stephen F. Kralik, Fernando Scaglia   +11 more
wiley   +1 more source