Results 11 to 20 of about 3,859 (182)

Deep Phenotyping of F64L Mutation in a Multicentric Cohort of Patisiran-Treated Hereditary Transthyretin Amyloidosis Patients (Patisiranitaly). [PDF]

Eur J Neurol
ABSTRACT Background The F64L variant is among the most frequent TTR mutations in Italy, typically associated with a predominantly neurologic phenotype and limited cardiac involvement. Methods Data from 181 ATTRv patients in the multicenter Patisiranitaly database treated with Patisiran since 2020 were analyzed. Neurologic impairment scores, Norfolk QoL‐
Ceccanti M, Guaraldi P, Romano A, Antonini G, Barilaro A, Briani C, Burattini M, Gianoli M, Carlini G, Cianci V, Dossi MC, Di Lisi D, Di Muzio A, Ratti A, Filosto M, Gasverde S, Gemelli C, Gentile L, Goglia M, Leonardi L, Longhi S, Lotti A, Manganelli F, Mazzeo A, Augello SM, Milella G, Novo G, Pareyson D, Fenu S, Palumbo G, Petrelli C, Poli L, Pradotto LG, Russo M, Salvalaggio A, Sciarrone MA, Sellitti L, Tagliapietra M, Tozza S, Castiglia M, Turri M, Verriello L, Chimenti C, Vitali F, Brighina F, Rini N, Inghilleri M, D'Angelo R, Abelardo D, Cambieri C, Libonati L, Moret F, Luigetti M, Di Stefano V.   +53 more
europepmc   +2 more sources

Direct Thrombectomy vs. Combined Treatment With Intravenous Thrombolysis in the Extended Time Window: A Target Trial Emulation. [PDF]

Eur J Neurol
This target‐trial emulation compared direct MT (n = 212) vs. IVT + MT (n = 135) in anterior‐circulation LVO patients treated 4.5–24 h or at wake‐up, eligible for IVT with perfusion mismatch. Using IPW with a non‐inferiority margin RD ≥ −1.3% for 90‐day mRS 0–2, direct MT was not non‐inferior to IVT + MT (adjRD −2.9%, 95% CI −6.64 to 0.84).
Nicolini E, Ciacciarelli A, Pracucci G, Saia V, Simonetti L, Zini A, Da Ros V, D'agostino F, Iacobucci M, De Michele M, Andrighetti M, Tassi R, Saletti A, Casetta I, Fainardi E, Pauciulo A, Caggiula M, Menozzi R, Pezzini A, Vallone S, Bigliardi G, Zimatore DS, Petruzzellis M, Comai A, Franchini E, Allegretti L, Tassinari T, Limbucci N, Nencini P, Carità G, Russo M, Filizzolo M, Mannino M, Ruggiero M, Longoni M, Boghi A, Naldi A, Bergui M, Bosco G, Pelle G, Alessiani M, Alberti M, Invernizzi P, Augelli R, Cappellari M, Lazzarotti GA, Giannini N, Konda D, Sallustio F, Mangiafico S, Toni D, IRETAS group.   +51 more
europepmc   +2 more sources

Lo studio della relazione attore-spettatore e i nuovi modelli cognitivi

Antropologia e Teatro, 2013
– IT Lo studio della relazione attore-spettatore può essere oggi approfondita alla luce dei nuovi modelli cognitivi. Questi modelli, legati in diversi modi alle proposte di embodied mind e alla neurofenomenologia introdotta da Varela negli anni ’90 ...
Gabriele Sofia
doaj   +1 more source

ERK pathway activation bidirectionally affects visual recognition memory and synaptic plasticity in the perirhinal cortex

Frontiers in Behavioral Neuroscience, 2011
ERK 1,2 pathway mediates experience-dependent gene transcription in neurons and several studies have identified its pivotal role in experience-dependent synaptic plasticity and in forms of long term memory involving hippocampus, amygdala or striatum. The
Davide eSilingardi, Andrea eAngelucci, Roberto eDe Pasquale, Marco eBorsotti, Giovanni eSquitieri, Riccardo eBrambilla, Elena ePutignano, Tommaso ePizzorusso, Tommaso ePizzorusso, Nicoletta eBerardi, Nicoletta eBerardi   +10 more
doaj   +1 more source

Longevity and health expectancy in an ageing society: implications for public health in Italy

Annali dell'Istituto Superiore di Sanità, 2012
INTRODUCTION: While the prolongation of life expectancy is due to medical, economic, social and public health advancements, longevity may not necessarily be an indicator of real development. Epidemiologic data indicate, in fact, that advanced age carries
Marianna Noale, Federica Limongi, Emanuele Scafato, Stefania Magg, Gaetano Crepaldi   +4 more
doaj   +1 more source

CACNA1A-p.Thr501Met mutation associated with familial hemiplegic migraine: a family report

The Journal of Headache and Pain, 2021
Background and aims Hemiplegic migraine (HM) is a rare form of migraine characterized by the presence of a motor and other types of aura. HM can be sporadic or familial.
Marina Romozzi, Guido Primiano, Eleonora Rollo, Lorena Travaglini, Paolo Calabresi, Serenella Servidei, Catello Vollono   +6 more
doaj   +1 more source

Cortico-Subcortical White Matter Bundle Changes in Cervical Dystonia and Blepharospasm

Biomedicines, 2023
Dystonia is thought to be a network disorder due to abnormalities in the basal ganglia-thalamo-cortical circuit. We aimed to investigate the white matter (WM) microstructural damage of bundles connecting pre-defined subcortical and cortical regions in ...
Costanza Giannì, Claudia Piervincenzi, Daniele Belvisi, Silvia Tommasin, Maria Ilenia De Bartolo, Gina Ferrazzano, Nikolaos Petsas, Giorgio Leodori, Nicoletta Fantoni, Antonella Conte, Alfredo Berardelli, Patrizia Pantano   +11 more
doaj   +1 more source

Per uno sposalizio tra neuro-cognitivismo e critica computazionale: l’esempio del gender

Testo & Senso, 2021
La critica computazionale negli ultimi vent’anni si è dimostrata un modello di distant reading funzionale alla ricerca di costanti morfologiche e archetipi tematici: con Franco Moretti ha addirittura nutrito l’ambizione, applicandosi alle Pathosformeln ...
Stefano Calabrese
doaj  

Novels in Augmented Reality

Between, 2014
One of the new forms of storytelling is immersive fiction, a narrative where the text creates events in a simulated world and in which the user is to govern a character or to identify with him, as in a video game.
Stefano Calabrese
doaj   +1 more source

Transcranial Photobiomodulation for the Treatment of Children with Autism Spectrum Disorder (ASD): A Retrospective Study

Children, 2022
Children with Autism Spectrum Disorder (ASD) face several challenges due to deficits in social function and communication along with restricted patterns of behaviors. Often, they also have difficult-to-manage and disruptive behaviors.
Stefano Pallanti, Michele Di Ponzio, Eleonora Grassi, Gloria Vannini, Gilla Cauli   +4 more
doaj   +1 more source