Results 31 to 40 of about 12,729 (175)

Interaction with NEGR1 affects mGlu5 cell signalling and the neuroprotection induced by the positive allosteric modulator VU0409551

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The metabotropic glutamate receptor mGlu5 plays an important role in neuronal survival and synaptic plasticity. We and others have shown that mGlu5 positive allosteric modulators (PAMs) are biased agonists, triggering the activation of neuroprotective pathways and promoting neuronal survival. As mGlu5 biased pharmacology
Jennifer D. S. Guimaraes, Toniana G. Carvalho, Luan A. Pereira, Emanuele G. Silva, Esther M. A. Maciel, Gabriella P. Torres, Thiago Assis, Pablo L. Cardozo, Joao P. P. de Almeida, Nathalia C. Silva, Francesca Pischedda, Giovanni Piccoli, Luciene B. Vieira, Juliana Alves‐Silva, Fabiola M. Ribeiro   +14 more
wiley   +1 more source

Neuroscienze, Scienze Umane e Pedagogia: quale rapporto? Prospettive e limiti delle Neuroscienze

Studi sulla Formazione, 2011
Neuroscience is the field that attempts to link psychological processes to brain activity. Classic neuropsychological approaches and powerful new techniques supported by rigorous methodological procedures enable neuroscientists to reveal the neuronal ...
Andrea Peru
doaj   +1 more source

The capacity of action observation to drag the trainees' motor pattern toward the observed model

Scientific Reports, 2023
Action Observation Training (AOT) promotes the acquisition of motor abilities. However, while the cortical modulations associated with the AOT efficacy are well known, few studies investigated the AOT peripheral neural correlates and whether their ...
Maria Chiara Bazzini, Arturo Nuara, Giulio Branchini, Doriana De Marco, Laura Ferrari, Maria Chiara Lanini, Simone Paolini, Emilia Scalona, Pietro Avanzini, Maddalena Fabbri-Destro   +9 more
doaj   +1 more source

Development of a machine learning (ML) model to predict 3‐month response to CGRP monoclonal antibodies in migraine: A pilot evaluation of physician‐ML model interaction

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Monoclonal antibodies that target calcitonin gene‐related peptide (CGRP‐mAbs) are effective treatments for preventing migraine in many patients but are expensive, and physicians cannot easily predict which patients will benefit from them.
Masahito Katsuki, Muneto Tatsumoto, Tomokazu Shimazu, Yasuhiko Matsumori, Marina Romozzi, Omid Kohandel Gargari, Alicia Gonzalez‐Martinez, Woo‐Seok Ha, Yutaro Fuse, Shiho Suzuki, Saro Kobayashi, Tomohiko Shiina, Mukuto Shioda, Hiroaki Fujita, Koichi Hirata, Yuya Kano, Ryosuke Fukazawa, Jackson T. S. Cheung, Siobhán O'Connor, Tomás Ward, Kieran Moran, Keisuke Suzuki   +21 more
wiley   +1 more source

Sessualità traumatica: un dialogo tra neuroscienze e psicoanalisi

Ricerca Psicoanalitica
Questo articolo esplora la complessa relazione tra l’abuso sessuale durante l’infanzia e lo sviluppo di disfunzioni sessuali nell’età adulta, attraverso una prospettiva integrata che unisce psicoanalisi, neuroscienze e sessuologia.
Chiara Soligo
doaj   +1 more source

Amore e neuroscienze

Rivista Internazionale di Filosofia e Psicologia, 2013
Love and the Neurosciences - In my paper I take on two tasks. First, I examine some recent publications which take a largely neuroscientific perspective on the topic of “love”.
Adriano Fabris
doaj   +1 more source

A Repertoire of Virtual-Reality, Occupational Therapy Exercises for Motor Rehabilitation Based on Action Observation

Data, 2022
There is a growing interest in action observation treatment (AOT), i.e., a rehabilitative procedure combining action observation, motor imagery, and action execution to promote the recovery, maintenance, and acquisition of motor abilities.
Emilia Scalona, Doriana De Marco, Maria Chiara Bazzini, Arturo Nuara, Adolfo Zilli, Elisa Taglione, Fabrizio Pasqualetti, Generoso Della Polla, Nicola Francesco Lopomo, Maddalena Fabbri-Destro, Pietro Avanzini   +10 more
doaj   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

The Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato, Lorenzo Santini, Raffaele Coppini, Eleonora Grandi   +3 more
wiley   +1 more source

Neuroscienze e lettura

Enthymema, 2013
La cosiddetta neurolettura, ossia l'indagine dell'attività del leggere alla luce delle neuroscienze, può dirsi iniziata già alla fine dell'Ottocento, tuttavia solo in tempi recenti si sono compiute importanti scoperte grazie alle tecniche di neuroimaging.
Federica Fioroni
doaj   +1 more source

Lines of interaction between training and cognitive neuroscience in application direction

Formare, 2017
Education Sciences require interdisciplinarity, self-reflective processes and evidence based research (Calvani, 2011; 2012a; 2012b; Margiotta, 2012; Trinchero, 2002; 2015) to overcome the oscillation, considered stalemate, between two types of ...
Luisa Salmaso
doaj   +1 more source