Results 91 to 100 of about 12,549 (250)

Androgen Regulation of the Mesocorticolimbic System and Executive Function

open access: yesFrontiers in Endocrinology, 2018
Multiple lines of evidence indicate that androgens, such as testosterone, modulate the mesocorticolimbic system and executive function. This review integrates neuroanatomical, molecular biological, neurochemical, and behavioral studies to highlight how ...
Daniel J. Tobiansky   +8 more
doaj   +1 more source

Pharmacological effect of one icv dose of Allopregnanolone in female rat: behavioural profile [PDF]

open access: yes, 2015
We have previously observed that intracerebroventricular allopregnanolone (ALLO) injection produced an anxiolytic effect and inhibited sexual receptivity when the test was performed in a separate manner. Also, ALLO reverts learning deficit in female rats
Cabrera Kreiker, Ricardo Jorge   +5 more
core  

Androgenetic alopecia: a review [PDF]

open access: yes, 2017
Purpose Androgenetic alopecia, commonly known as male pattern baldness, is the most common type of progressive hair loss disorder in men. The aim of this paper is to review recent advances in understanding the pathophysiology and molecular mechanism
Caro, Gemma   +7 more
core   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

open access: yesIbrain, Volume 12, Issue 1, Page 96-122, Spring 2026.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard   +2 more
wiley   +1 more source

Safety and efficacy of zuranolone in Japanese adults with major depressive disorder: An open‐label, repeated‐treatment part of a Phase 3 clinical trial

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Aim To evaluate the safety and tolerability of repeating 14‐day treatment with zuranolone (30 mg) followed by a 6‐week follow‐up period (one treatment cycle) for a maximum of six treatment cycles in Japanese participants with major depressive disorder. Methods This multicenter Phase 3 study was conducted in two parts (70 sites; Japan).
Masaki Kato   +8 more
wiley   +1 more source

Steroidogenic acute regulatory (StAR) protein expression in the central nervous system

open access: yesFrontiers in Endocrinology, 2011
Locally produced neurosteroids are proposed to have many functions in the central nervous system. The identification of the steroidogenic acute regulatory (StAR) protein in steroid-producing neural cells provides a new tool to understand the sites ...
Steven R. King, Douglas M Stocco
doaj   +1 more source

Analgesic and Anti-Inflammatory Effects of the Synthetic Neurosteroid Analogue BNN27 during CFA-Induced Hyperalgesia [PDF]

open access: gold, 2021
Smaragda Poulaki   +4 more
openalex   +1 more source

Dehydroepiandrosterone sulfate (DHEAS) is neuroprotective when administered either before or after injury in a focal cortical cold lesion model [PDF]

open access: yes, 2006
Dehydroepiandrosterone and its sulfate (DHEAS) are sex hormone precursors that exert marked neurotrophic and/or neuroprotective activity in the central nervous system.
Dobszay B., Gábor   +8 more
core  

Delta-subunit-containing GABAA-receptors mediate tonic inhibition in paracapsular cells of the mouse amygdala [PDF]

open access: yes, 2014
The intercalated paracapsular cells (pcs) are small GABAergic interneurons that form densely populated clusters surrounding the basolateral (BLA) complex of the amygdala.
Anne Marowsky, Kaspar E. Vogt
core   +2 more sources

Analysis of depressive symptom trajectory patterns with zuranolone: Time‐series clustering of Japanese Phase 2 and Phase 3 trial data

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
In this pooled analysis of Phase 2/3 trials in Japanese adults with major depressive disorder (MDD), we aimed to characterize depressive symptom trajectories following zuranolone 30 mg administration. Dynamic Time Warping–based k‐means clustering identified four distinct symptom trajectories.
Masaki Kato   +5 more
wiley   +1 more source

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