Results 101 to 110 of about 12,549 (250)
The Sooner, the Better: Neuroprotective Strategies in Fetuses With Congenital Heart Disease
Prenatal Diagnosis, Volume 46, Issue 3, Page 368-381, March 2026.ABSTRACT Congenital heart disease (CHD) is the most frequent congenital malformation at birth and is associated with neurodevelopmental impairments. Alterations in cardiovascular physiology can lead to reduced cerebral blood perfusion and oxygenation, which negatively affects brain growth and maturation.
Maaike Nijman +7 more
wiley +1 more source
YAKUGAKU ZASSHI, 1997 The term neurosteroids applies to those steroids that are both synthesized in the nervous system, either de novo from cholesterol or from steroid hormone precursors, and that accumulate in the nervous system to levels that are at least in part independent of steroidogenic gland secretion rates.
openaire +3 more sources
Neurosteroid Actions in Memory and Neurologic/Neuropsychiatric Disorders
Frontiers in Endocrinology, 2019 Memory dysfunction is a symptomatic feature of many neurologic and neuropsychiatric disorders; however, the basic underlying mechanisms of memory and altered states of circuitry function associated with disorders of memory remain a vast unexplored ...
Marcia H. Ratner +2 more
doaj +1 more source
Frontiers in Pharmacology, 2018 The translocator protein (18 kDa) (TSPO) recently attracted increasing attention in the pathogenesis of post-traumatic stress disorder (PTSD). This study is testing the hypothesis that the overexpression of TSPO in hippocampus dentate gyrus (DG) could ...
Xiao-Ying Zhang +7 more
doaj +1 more source
The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis. [PDF]
, 2016 The mitochondrial translocator protein (TSPO) has been implicated in CNS diseases. Here, we sought to determine the specific role of TSPO in experimental autoimmune encephalomyelitis (EAE), the most studied animal model of multiple sclerosis (MS).
Chechneva, Olga +3 more
core +1 more source
Outlook Magazine, Winter 2018 [PDF]
, 2018 https://digitalcommons.wustl.edu/outlook/1206/thumbnail ...
core +1 more source
Robust photoregulation of GABA(A) receptors by allosteric modulation with a propofol analogue. [PDF]
, 2012 Photochemical switches represent a powerful method for improving pharmacological therapies and controlling cellular physiology. Here we report the photoregulation of GABA(A) receptors (GABA(A)Rs) by a derivative of propofol (2,6-diisopropylphenol), a ...
Bruzik, Karol S +8 more
core +2 more sources
Thyroid hormones modulate GABA(A) receptor-mediated currents in hippocampal neurons( 2011) . [PDF]
, 2011 Thyroid hormones (THs) play a crucial role in the maturation and functioning of mammalian central nervous system. Thyroxine (T4) and 3, 3', 5-L-triiodothyronine (T3) are well known for their genomic effects, but recently attention has been focused on ...
Losi G., PUJA, Giulia
core +1 more source