INCREASED NEUROSTEROID SYNTHETIC CAPACITY OF THE PLACENTA PROTECTS THE FEMALE FETUS FROM THE EFFECTS OF MATERNAL STRESS IN GUINEA PIGS [PDF]
, 2019 openalex +1 more source
The major brain cholesterol metabolite 24(s)-hydroxycholesterol is a potent allosteric modulator of N-methyl-d-aspartate receptors [PDF]
, 2013 N-methyl-d-aspartate receptors (NMDARs) are glutamate-gated ion channels that are critical to the regulation of excitatory synaptic function in the CNS.
Belfort, Gabriel M +11 more
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Frontiers in Physiology, 2019 Children born preterm are at an increased risk of developing cognitive problems and neuro-behavioral disorders such as attention deficit hyperactivity disorder (ADHD) and anxiety. Whilst neonates born at all gestational ages, even at term, can experience
Julia C. Shaw +11 more
doaj +1 more source
Fetal Alcohol Exposure Alters Neurosteroid Modulation of Hippocampal N-Methyl-d-aspartate Receptors [PDF]
, 2000 Edmar Tavares da Costa +8 more
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Brain and BehaviorBackground Preterm birth is associated with brain injury and long‐term behavioral abnormalities, for which there are limited prevention options. When born preterm, infants prematurely lose placental neurosteroid (allopregnanolone) support. This increases
Roisin A. Moloney +4 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2016 Catamenial epilepsy is a complex neuroendocrine condition in which seizures are clustered around specific points in the menstrual cycle, most often around perimenstrual or periovulatory period.
Doodipala Samba eReddy
doaj +1 more source
Estradiol synthesis and action at the synapse: evidence for ‘synaptocrine’ signaling
Frontiers in Endocrinology, 2011 Classically, the modulation of brain function and behavior by steroid hormones was linked exclusively to secretion by peripheral endocrine glands. Subsequently, steroid actions within the brain were shown dependent upon either synthesis and secretion by ...
Luke eRemage-Healey +2 more
doaj +1 more source
A Pilot Stability Study of Dehydroepiandrosterone Rapid-dissolving Tablets Prepared by Extemporaneous Compounding [PDF]
, 2017 Dehydroepiandrosterone supplementation is used to treat a variety of conditions. Rapid-dissolving tablets are a relatively novel choice for compounded dehydroepiandrosterone dosage forms. While rapid-dissolving tablets offer ease of administration, there
Rush, Steven D. +2 more
core +1 more source
Novel neurosteroid hypnotic blocks T-type calcium channel-dependent rebound burst firing and suppresses long-term potentiation in the rat subiculum [PDF]
, 2019 Srdjan M. Joksimovic +9 more
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Emotional brain activation across the menstrual cycle in women with premenstrual dysphoric disorder and associations to serum levels of progesterone-derived neurosteroids [PDF]
, 2022 Louise Stiernman +6 more
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