Results 41 to 50 of about 1,686,973 (307)

Variation in academic neurosurgery departments’ #neurosurgery social media influence

World Neurosurgery: X, 2023
Background: Social media use is increasingly common among academic neurosurgery departments, but its relationship with academic metrics remains underexamined. Methods: We examine the relationship between American academic neurosurgery departments’ number
Michael B. Cloney, Benjamin Hopkins, Anastasios Roumeliotis, Najib El Tecle, Nader S. Dahdaleh   +4 more
doaj   +1 more source

Machine learning in neurosurgery: a global survey [PDF]

, 2020
Background: Recent technological advances have led to the development and implementation of machine learning (ML) in various disciplines, including neurosurgery.
van Niftrik, C.H.B. (Christiaan H. B.), Stumpo, V, Kernbach, Julius M., Stienen, M.N., Stienen, MN, Schröder, Marc L., Schröder, Marc L, Klukowska, Anita M, Klukowska, AM, Veeravagu, A. (Anand), Regli, L, Kernbach, J.M., Stienen, Martin N., Serra, Carlo, Serra, C., Stienen, M.N. (Martin N.), Staartjes, Victor E; https://orcid.org/, Schröder, ML, Stumpo, V., van Niftrik, Christiaan H.B., Gadjradj, Pravesh S., Veeravagu, A., Klukowska, A.M., Serra, Carlo; https://orcid.org/, Veeravagu, A, van Niftrik, CHB, Gadjradj, Pravesh, Regli, Luca, Staartjes, V.E. (Victor E.), Regli, L., Regli, L. (Luca), Schroder, M.L., Klukowska, A.M. (Anita M.), Serra, C, Niftrik, C.H.B. van, Schröder, M.L. (Marc L.), Staartjes, Victor E., Kernbach, JM, Stumpo, Vittorio, Klukowska, Anita M., Veeravagu, Anand, Kernbach, J.M. (Julius M.), Serra, C. (Carlo), Gadjradj, P.S. (Pravesh S.), Gadjradj, P.S., Gadjradj, Pravesh S, Kernbach, Julius M, van Niftrik, Christiaan H B; https://orcid.org/, Gadjradj, Pravesh; id_orcid, Stienen, Martin N; https://orcid.org/, Stumpo, V. (Vittorio), Staartjes, VE, Staartjes, V.E.   +52 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The 150th anniversary of Nagasaki University School of Medicine: recovery from the atomic disaster and evolution of the department of neurosurgery. [PDF]

, 2009
NAGASAKI IS LOCATED on the western edge of Japan, closer to the Asian continent. Because of this geographical proximity, Nagasaki became a gateway for the introduction of continental culture and civilization to Japan.
Nagata, Izumi, Suyama, Kazuhiko, Hayashi, Kentaro, Matsuo, Takayuki, Kitagawa, Naoki, Ushijima, Ryujiro   +5 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Standards for reporting randomized controlled trials in neurosurgery

, 2011
Object The Consolidated Standards for Reporting of Trials (CONSORT) criteria were published in 1996 to standardize the reporting and improve the quality of clinical trials.
Dumont, Aaron S, Aaron S. Dumont, Starke, Robert M, Pouratian, Nader, Nader Pouratian, Robert M. Starke, Kiehna, Erin N, Erin N. Kiehna   +7 more
core   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Exploring the landscape of machine learning applications in neurosurgery: A bibliometric analysis and narrative review of trends and future directions

, 2023
The field of neurosurgery has consistently represented an area of innovation and integration of technology since its inception. As such, machine learning (ML) has found its way into applications within neurosurgery relatively rapidly.
Bhatia, Shovan, Levy, Adam S., Rivera, Cameron A., Di, Long, Merenzon, Martin A., Andryski, Allie L., Komotar, Ricardo J., Ivan, Michael E., Daggubati, Lekhaj, Shah, Ashish H.   +9 more
core   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source