Results 211 to 220 of about 1,701,414 (246)
Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho +6 more
wiley +1 more source
Annals of Neurology, Volume 100, Issue 5, Page 948-961, November 2026.Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl +10 more
wiley +1 more source
Brain and Behavior, Volume 16, Issue 11, November 2026.This study developed and validated a machine learning‐based prediction model for postoperative hydrocephalus following aneurysmal subarachnoid hemorrhage (aSAH). Using retrospective data from 331 patients, we identified four key predictors: admission GCS score, admission Hunt‐Hess grade, intraoperative external ventricular drainage (EVD), and ...
Fuguang Li +9 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 11, November 2026.ABSTRACT Secondary infection can coexist with and obscure an underlying soft‐tissue sarcoma. A deep mass that persists or progresses despite drainage and appropriate antibiotics, especially with progressive neurological deficit, warrants image‐guided core biopsy and sarcoma‐center referral before further surgery.
Baraa Nassar +4 more
wiley +1 more source
Intratumoral and Peritumoral Functional Connectivity Reveals Network‐Level Signatures of Glioma
MedComm, Volume 7, Issue 11, November 2026.Using resting‐state fMRI in 306 glioma patients, this study maps individualized intra‐ and peritumoral functional networks. Novel metrics (RIFR, RPTR) quantify tumor‐related network remodeling, correlating with pathology, structure, cognition, and survival. A prognostic model incorporating these network features achieves an AUC of 0.90.
Hongbo Bao +24 more
wiley +1 more source
MedComm, Volume 7, Issue 11, November 2026.Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He +4 more
wiley +1 more source
Anaesthesia, Volume 81, Issue 11, Page 1497-1509, November 2026.Summary Introduction The Standardised Endpoints in Perioperative Medicine Initiative recommends the 12‐item WHO Disability Assessment Schedule (WHODAS) 2.0 to measure postoperative functional impairment. However, evidence describing long‐term postoperative disability, particularly at 1 year, remains limited.
Alexandra Stroda +33 more
wiley +1 more source
Anaesthesia, Volume 81, Issue 11, Page 1569-1580, November 2026.Summary Introduction The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) is recommended by peri‐operative core outcome sets as a measure of disability. Despite its growing use, the effect of different surgical procedures on disability measured by WHODAS 2.0 remains poorly understood and heterogeneous reporting across studies ...
Romijn M. Boerlage +7 more
wiley +1 more source