The optimum condition of the toluidine red unheated serum test for the replacement of the venereal disease research laboratory test in cerebrospinal fluid for neurosyphilis diagnosis [PDF]
Background: The cerebrospinal fluid (CSF) venereal disease research laboratory (VDRL) test remains the standard for the laboratory diagnosis of neurosyphilis.
Yao Xiao +5 more
doaj +2 more sources
Latent class analysis and machine learning for clinical subtyping prediction and differentiation in suspected neurosyphilis patients [PDF]
ObjectiveNeurosyphilis presents significant diagnostic and therapeutic challenges due to its heterogeneous clinical manifestations, absence of a gold-standard diagnostic criterion, and variable treatment responses.
Sirui Wu +6 more
doaj +2 more sources
The relationships of renal function markers with disease activities and neurosyphilis in HIV-negative patients with syphilis [PDF]
Objectives To investigate the associations between renal function markers and disease activities and neurosyphilis in patients with syphilis. Methods A total of 390 HIV-negative syphilis patients were included in the study. Serum blood urea nitrogen (BUN)
Fanghua He +10 more
doaj +2 more sources
Neurosyphilis Presenting as Sleep Disorder and Muscle Soreness Complicated With HIV Infection: A Case Report [PDF]
Neurosyphilis is a tertiary syphilis complication or manifestation caused by Treponema pallidum, which invades the central nervous system. Its clinical manifestations are often nonspecific.
Shu-Qi Yang +5 more
doaj +2 more sources
Evaluation of cerebrospinal fluid treponema pallidum particle agglutination assay titer for neurosyphilis diagnosis among HIV-negative syphilis patients [PDF]
PurposeThe study aimed to assess the association between CSF-TPPA titer and the presence of neurosyphilis, and to determine the optimal CSF-TPPA titer cutoff for diagnosing neurosyphilis.MethodsWe conducted a cross-sectional study at a single center from
Mei Shi +10 more
doaj +2 more sources
Neurosyphilis with dementia and bilateral hippocampal atrophy on brain magnetic resonance imaging [PDF]
Background This article reports a rare case of active neurosyphilis in a man with mild to moderate dementia and marked hippocampal atrophy, mimicking early onset Alzheimer’s disease. Few cases have so far described bilateral hippocampal atrophy mimicking
Mehrabian Shima +6 more
doaj +2 more sources
Meningovascular neurosyphilis with basilar artery thrombosis in HIV patient
Currently, neurosyphilis is an uncommon disease and may occur at any stage of syphilis. Co-infection of syphilis with HIV can affect the clinical course.
Edgar Perez Barragán +3 more
doaj +2 more sources
Neurosyphilis with optical involvement in an immunocompetent patient: a case report
Rui Paulo Rodrigues, Nuno Correia, António Vieira LopesInternal Medicine Service, Saint John Hospital Center, Porto, PortugalBackground: Neurosyphilis became a rare disease after the introduction of antibiotics.
Correia N, Rodrigues RP, Lopes AV
doaj +3 more sources
Possibilities of magnetic resonance tomography in identification and diagnostics of neurosyphilis forms [PDF]
Aim: To evaluate the possibilities of the magnetic resonance tomography (MRT) in diagnostics and identification of neurosyphilis. Materials and methods: A total of 1387 patients with different forms of documented neurosyphilis were examined to study the ...
Kolokolov O.V. +7 more
doaj +2 more sources
BackgroundIn recent years, the incidence of syphilis has increased year by year. Our study is to explore the risk factors for the development of neurosyphilis in patients who failed syphilis treatment.MethodsA total number of 165 patients with complete ...
Wenying Cui +5 more
doaj +1 more source

