Neurosyphilis in China: A Systematic Review of Cases From 2009–2021
Frontiers in Medicine, 2022 Considered the increased threaten of neurosyphilis in China, a review on cases reported in the literature to describe the clinical epidemiological characteristics of neurosyphilis cases, may be beneficial to the early detection and management strategies ...
Rui-Li Zhang +2 more
exaly +3 more sources
Advances in laboratory diagnostic methods for cerebrospinal fluid testing for neurosyphilis
Frontiers in Public Health, 2022 Neurosyphilis is a chronic infectious disease caused by the invasion of Treponema pallidum into the central nervous system. In recent years, with the increase in the latent syphilis infection rate, the incidence of neurosyphilis has gradually increased ...
Yu Gou, Liu Xiao-Qin
exaly +3 more sources
An Updated Review of Recent Advances in Neurosyphilis
Frontiers in Medicine, 2022 Neurosyphilis is caused by Treponema pallidum invading the central nervous system, of which the incidence is increasing worldwide. Due to its variable clinical manifestations, diagnosis of neurosyphilis remains challenging, especially the asymptomatic ...
Hanlin Zhang, Zhang Hanlin
exaly +3 more sources
Chronic Subdural Hematoma in a Patient With Long-Standing Syphilis. [PDF]
Clin Case RepABSTRACT Chronic subdural hematoma can rarely occur in younger adults without trauma or coagulopathy. Comprehensive imaging to exclude vascular malformations, combined with burr hole evacuation and middle meningeal artery embolization, can achieve excellent outcomes.
Marino J +3 more
europepmc +2 more sources
Neurosyphilis Presenting With Subtle Clinical Features: A Diagnostic and Therapeutic Challenge. [PDF]
Case Rep Neurol MedWe report the case of a 36‐year‐old male who presented with an acute onset of headache, vomiting, and feverish sensation with a history of prior unsafe sexual activity. VDRL and TPHA were reactive in both the blood and cerebrospinal fluid. A diagnosis of neurosyphilis was thus made, and we successfully treated the patient with ceftriaxone and ...
Shahi T +6 more
europepmc +2 more sources
Clinical presentation of neurosyphilis – a single-center retrospective data analysis [PDF]
Neurological Research and PracticeBackground As cases of neurosyphilis are rising worldwide – especially in people living with HIV (PLWH) – current data on clinical presentation, diagnostics and management of neurosyphilis in Europe are of high interest.
Susanne Dyckhoff-Shen +5 more
doaj +2 more sources
Treponema pallidum’s neural invasion: from blood-brain barrier breach to immune sabotage [PDF]
Infection and ImmunityNeurosyphilis is an infectious disease of the nervous system caused by Treponema pallidum. With the resurgence of syphilis worldwide, neurosyphilis has become prevalent again, but research on its pathogenesis remains challenging. T.
Han Yu +7 more
doaj +2 more sources
Prevalence of Neurosyphilis in Patients with Acute Ischemic Stroke: A Cross-Sectional Screening Study in Thailand [PDF]
Tropical Medicine and Infectious DiseaseMeningovascular syphilis, a type of neurosyphilis, causes stroke and various types of myelopathy. In recent years, there has been an increase in the incidence of neurosyphilis.
Chumpol Anamnart, Nawanwat Tepkidakarn
doaj +2 more sources
Latent class analysis and machine learning for clinical subtyping prediction and differentiation in suspected neurosyphilis patients [PDF]
Frontiers in Cellular and Infection MicrobiologyObjectiveNeurosyphilis presents significant diagnostic and therapeutic challenges due to its heterogeneous clinical manifestations, absence of a gold-standard diagnostic criterion, and variable treatment responses.
Sirui Wu +6 more
doaj +2 more sources
The relationships of renal function markers with disease activities and neurosyphilis in HIV-negative patients with syphilis [PDF]
European Journal of Medical ResearchObjectives To investigate the associations between renal function markers and disease activities and neurosyphilis in patients with syphilis. Methods A total of 390 HIV-negative syphilis patients were included in the study. Serum blood urea nitrogen (BUN)
Fanghua He +10 more
doaj +2 more sources