Results 101 to 110 of about 171,196 (309)

Negative myoclonus as a manifestation of cefepime neurotoxicity

Clinical Case Reports
Key Clinical Message Negative myoclonus may present in the early stages of cefepime neurotoxicity. Cefepime neurotoxicity typically presents as reduced consciousness, myoclonus, and seizures; however, negative myoclonus is uncommon.
Daichi Umemoto, Hirokazu Kuroda, Hiroaki Nishioka   +2 more
doaj   +1 more source

Short-course metronidazole-induced reversible acute neurotoxicity in a renal transplant recipient

Saudi Journal of Kidney Diseases and Transplantation, 2018
Neurotoxic manifestations due to chronic metronidazole intake are well known, but neurotoxicity due to short-term use of metronidazole is very rare. We present a case of acute neurotoxicity due to short course of injectable metronidazole given in usual ...
Pavitra Manu Dogra, Anil Kumar Bhatt, Sanjay Kumar Agarwal, Dipankar Bhowmik   +3 more
doaj   +1 more source

Fluvoxamine alleviates paclitaxel-induced neurotoxicity [PDF]

, 2015
Paclitaxel (Px) is an effective chemotherapeutic agent for the treatment of various cancers. However, it is often associated with neurological side effects, including chemotherapy-associated cognitive impairment (CACI), such as “chemobrain”.
Kudo, Takashi, Tanimukai, Hitoshi
core   +1 more source

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

Advanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen, Yao Zhao, Yangye Lian, Yifei Hou, Lifen Gong, Tingting Wu, Yulin Yang, Jiaqi Zhu, Xin Wang, Kaihua Zhang, Jing Ding   +10 more
wiley   +1 more source

Child with acute methotrexate related neurotoxicity: Can diffusion weighted MRI help??

The Egyptian Journal of Radiology and Nuclear Medicine, 2015
Background: Methotrexate is widely used chemotherapy especially in pediatric hematological malignancy. It may associate with acute neurotoxicity.
Ayda A. Youssef, Tarek A. Raafat, Youssef Madney   +2 more
doaj   +1 more source

Lithium Associated Side Effects and Neurotoxicity: Is Lithium Neurotoxicity Related to Iron Deposition? [PDF]

, 2019
Lithium is a mood stabilizer that Australian psychiatrist John Cade and the Swiss Baastrup and Schou’s pioneering studies brought in the treatment of bipolar disorder.
Kılıç, Neslihan, Murat İlhan Atagün, Atagün, Murat İlhan, Yıldızoğlu, Emrah, Neslihan Kılıç, Altun, İlkay Keleş, İlkay Keleş Altun, Emrah Yıldızoğlu   +7 more
core   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Microalgae Hybrid Biosystem for Enhanced Oral Delivery of Rifaximin in Hepatic Encephalopathy Treatment

Advanced Science, EarlyView.
The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang, Xueting Huang, Lingxiao Yang, Jin Liu, Lei Lei, Shaomin Zou, Kai Wang, Min Zhou, Zhe Tang   +8 more
wiley   +1 more source

Tuberculum sellae meningioma with possible tacrolimus neurotoxicity manifesting as manic-like psychosis after kidney transplantation

Annals of General Psychiatry, 2019
Background Although kidney transplantation is the best treatment option for chronic kidney disease, the accompanying immunosuppressive treatment can induce severe neurotoxicity presenting, on rare occasions, as psychosis.
Eun Hyun Seo, Seung-Gon Kim, Yong Soo Cho, Hyung-Jun Yoon   +3 more
doaj   +1 more source

Metronidazole-induced neurotoxicity: Is iron a contributing factor?

Metronidazole-induced neurotoxicity is a rising challenge in managing susceptible infections. The mechanisms involved in metronidazole-induced neurotoxicity are not fully unraveled.
Bariweni, M.W., Zariwala, M., Ozolua, R.I., Moses W. Bariweni, Patel, V.B.   +4 more
core   +1 more source