Results 181 to 190 of about 270,958 (352)

Neurotoxic Effects of Lipopolysaccharide on Nigral Dopaminergic Neurons Are Mediated by Microglial Activation, Interleukin-1β, and Expression of Caspase-11 in Mice [PDF]

, 2004
Hiroyuki Arai, Tsuyoshi Furuya, Toru Yasuda, Masayuki Miura, Yoshikuni Mizuno, Hideki Mochizuki   +5 more
openalex   +1 more source

Superoxide Dismutase 1 in Health and Disease: How a Frontline Antioxidant Becomes Neurotoxic [PDF]

, 2020
Benjamin G. Trist, James B. Hilton, Dominic J. Hare, Peter J. Crouch, Kay L. Double   +4 more
openalex   +1 more source

Neurotoxicity studies

Folia Pharmacologica Japonica, 2008
Hiroaki, Takahashi, Kohji, Takada
openaire   +3 more sources

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway [PDF]

, 2012
Ying Xu, Jianchun Pan, Ling Chen, Chong Zhang, Jiao Sun, Jianxin Li, Linda Nguyen, Neetu Nair, Hanting Zhang, James M. O’Donnell   +9 more
openalex   +1 more source

Astrocyte-microglia interaction promotes rotenone-induced dopaminergic neurotoxicity

, 2021
Ikuko Miyazaki, Ryo Kikuoka, Nami Isooka, Shinki Murakami, Chiharu Sogawa, Norio Sogawa, Yoshihisa Kitamura, Masato Asanuma   +7 more
openalex   +2 more sources

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Ceftazidime-Avibactam-Induced Neurotoxicity Manifesting as Seizure in an Older Adult: A Case Report. [PDF]

Infect Drug Resist
Li Z, Li C, Zhao P, Han Y, Lu N.
europepmc   +1 more source

Phase 1 results of ZUMA-1: A multicenter study of KTE-C19 anti-CD19 CAR T cell therapy in refractory aggressive lymphoma [PDF]

, 2017
Bartlett, Nancy L, et al,, Ghobadi, Armin   +2 more
core   +2 more sources

Neurotoxic, cytotoxic and cardiovascular effects of some Australasian elapid venoms

, 2017
Janeyuth Chaisakul
openalex   +1 more source