Results 231 to 240 of about 242,018 (356)
Food Science &Nutrition, Volume 11, Issue 1, Page 249-260, January 2023., 2023 This study indicated, for the first time, that (±) linalool and its enantiomer, (R)‐(‐) linalool protected PC12 cells against injury induced by oxygen and glucose deprivation/reoxygenation (OGD/R) via the mitigation of oxidative stress and the downregulation of Bax/Bcl‐2, caspase‐3 and caspase‐9, resulting in decreased apoptotic cell death.
Azar Hosseini +5 more
wiley +1 more source
Indole-3-acetic acid and chenodeoxycholic acid attenuate TLR4/NF-κB signaling and endoplasmic reticulum stress in valproic acid-induced neurotoxicity. [PDF]
Front PharmacolSarawi WS +9 more
europepmc +1 more source
Insulin and Metformin are Associated With Reduced Risk of Amyotrophic Lateral Sclerosis
Chronic Diseases and Translational Medicine, EarlyView.Human insulin heterodimer (A). Human insulin heterodimer (dark blue) docked within center of Cx43 channel (B) Abstract Background Type 2 diabetes (T2D), but not type 1, protected against amyotrophic lateral sclerosis (ALS). In T2D serum insulin is normal or elevated in the early stages.
Steven Lehrer, Peter H. Rheinstein
wiley +1 more source
Food Science &Nutrition, Volume 11, Issue 1, Page 443-457, January 2023., 2023 Acrylamide triggered macrophage cell apoptosis and autophagy and pyroptosis. ;P2X7 was of great significance in acrylamide‐induced cell death, but was mainly responsible for the regulation of autophagy and pyroptosis. Acrylamide stimulated oxidative stress via P2X7 in macrophage cells.
Jing Wang +5 more
wiley +1 more source
Anti-inflammatory effect of grounding mat on trimethyltin-induced neurotoxicity rats. [PDF]
J Exerc RehabilYe M +6 more
europepmc +1 more source
Lethal neurotoxicity associated to azidothymidine therapy. [PDF]
, 1989 Silvana Saracchini +5 more
openalex +1 more source
Synthesis and Biological Evaluation of Bicyclic Pyrazolines with Promising Antimicrobial Activities
ChemMedChem, Accepted Article.The efficient photochemical synthesis of bicyclic pyrazolines using flow technology as well as the subsequent antimicrobial evaluation of these scaffolds is reported. Low MIC values of 0.5‐4 μg/mL were found against a series of multidrug resistant bacterial strains including different Staphylococcus and Enterococcus genera species The lead compound ...
Debora Caviglia +4 more
wiley +1 more source
Deletion of MyD88 in astrocytes prevents β‐amyloid‐induced neuropathology in mice
Glia, Volume 71, Issue 2, Page 431-449, February 2023., 2023 Main Points MyD88 is upregulated in astrocytes in Alzheimer's disease. Deletion of MyD88 in astrocytes protects against β‐amyloid‐induced synaptic toxicity and cognitive impairment in mice. Abstract As the understanding of immune responses in Alzheimer's disease (AD) is in its early phases, there remains an urgency to identify the cellular and ...
Tee Jong Huat +8 more
wiley +1 more source
Neurological complications associated with chimeric antigen receptor T cell therapy. [PDF]
J Cereb Blood Flow MetabYan S, Zhou M, Zhu X, Xiao Y.
europepmc +1 more source