Results 361 to 370 of about 326,305 (400)
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Archives of Dermatology, 1972
To the Editor.— The neurotoxicity of sulfones is a recognized but rare untoward reaction. The following report illustrates a case of peripheral neuropathy as a complication of dapsone therapy of dermatitis herpetiformis. Report of a Case A 21-year-old white man from Wichita, Kan, has had dermatitis herpetiformis for three years characterized by an ...
Winthrope R. Hubler, Herman Solomon
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To the Editor.— The neurotoxicity of sulfones is a recognized but rare untoward reaction. The following report illustrates a case of peripheral neuropathy as a complication of dapsone therapy of dermatitis herpetiformis. Report of a Case A 21-year-old white man from Wichita, Kan, has had dermatitis herpetiformis for three years characterized by an ...
Winthrope R. Hubler, Herman Solomon
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2009
With the advent of effective treatment regimes increasing survival rates, delayed treatment-related cognitive dysfunction has been recognized as a significant problem. It is considered the most frequent complication among long-term survivors. WBRT may lead to deep brain atrophy and leukoencephalopathy associated with severe cognitive dysfunction ...
Uwe Schlegel, Pasquale Calabrese
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With the advent of effective treatment regimes increasing survival rates, delayed treatment-related cognitive dysfunction has been recognized as a significant problem. It is considered the most frequent complication among long-term survivors. WBRT may lead to deep brain atrophy and leukoencephalopathy associated with severe cognitive dysfunction ...
Uwe Schlegel, Pasquale Calabrese
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Toxicology Letters, 2010
Chemical susceptibility is triggered by a large range of chemicals present both indoors and outdoors including pesticides, cleaning products, perfumes, scented products and cigarette smoke. Health risk after chemical exposure depends on age, sex, genetic factors, socioeconomic status, nutritional status, and environmental factors.
Tin-Tin Win-Shwe, Hidekazu Fujimaki
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Chemical susceptibility is triggered by a large range of chemicals present both indoors and outdoors including pesticides, cleaning products, perfumes, scented products and cigarette smoke. Health risk after chemical exposure depends on age, sex, genetic factors, socioeconomic status, nutritional status, and environmental factors.
Tin-Tin Win-Shwe, Hidekazu Fujimaki
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Annals of Emergency Medicine, 1985
Meperidine neurotoxicity manifests as shakiness, tremors, myoclonus, and seizures. It is generally seen with repeated parenteral use. We report a case of meperidine neurotoxicity from oral use by an otherwise healthy woman. The pharmacology and clinical implications are discussed.
Michael J. Thirman, Mark G. Goetting
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Meperidine neurotoxicity manifests as shakiness, tremors, myoclonus, and seizures. It is generally seen with repeated parenteral use. We report a case of meperidine neurotoxicity from oral use by an otherwise healthy woman. The pharmacology and clinical implications are discussed.
Michael J. Thirman, Mark G. Goetting
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Nature Reviews Neuroscience, 2008
Neurons have a constantly high glucose demand, and unlike muscle cells they cannot accommodate episodic glucose uptake under the influence of insulin. Neuronal glucose uptake depends on the extracellular concentration of glucose, and cellular damage can ensue after persistent episodes of hyperglycaemia--a phenomenon referred to as glucose neurotoxicity.
Tomlinson, David R. +1 more
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Neurons have a constantly high glucose demand, and unlike muscle cells they cannot accommodate episodic glucose uptake under the influence of insulin. Neuronal glucose uptake depends on the extracellular concentration of glucose, and cellular damage can ensue after persistent episodes of hyperglycaemia--a phenomenon referred to as glucose neurotoxicity.
Tomlinson, David R. +1 more
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Neuropathology, 2001
After the discovery of 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP), we acquired a good animal model of Parkinson's disease. The extraordinary recent growth in knowledge using MPTP parkinsonism has fostered increased understanding of Parkinson's disease.
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After the discovery of 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP), we acquired a good animal model of Parkinson's disease. The extraordinary recent growth in knowledge using MPTP parkinsonism has fostered increased understanding of Parkinson's disease.
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Canadian Journal of Physiology and Pharmacology, 1984
Aluminum is the most abundant metal and the third most common element. Soluble aluminum salts can be absorbed from the stomach and the metal is deposited in the gray matter in the brain. Following exposure to aluminum, aggregates of neurofilaments accumulate in neurons.
L A Bates, R J Boegman
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Aluminum is the most abundant metal and the third most common element. Soluble aluminum salts can be absorbed from the stomach and the metal is deposited in the gray matter in the brain. Following exposure to aluminum, aggregates of neurofilaments accumulate in neurons.
L A Bates, R J Boegman
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Journal of Agromedicine, 2007
Several pesticides such as organophosphates, carbamates and the organochlorine pesticides directly target nervous tissue as their mechanism of toxicity. In several others, such as the fumigants, the nervous system is affected by toxicological mechanisms that diffusely affect most or all tissues in the body.
Jordan A. Firestone, Matthew C. Keifer
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Several pesticides such as organophosphates, carbamates and the organochlorine pesticides directly target nervous tissue as their mechanism of toxicity. In several others, such as the fumigants, the nervous system is affected by toxicological mechanisms that diffusely affect most or all tissues in the body.
Jordan A. Firestone, Matthew C. Keifer
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Acta Neurologica Scandinavica, 1983
Alterations in nervous system functioning following acute and chronic ethanol exposure have been studied in a great number of experimental investigations. Results from many of these investigations can be difficult to interpret, particularly since a variety of techniques and exposure models are employed.
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Alterations in nervous system functioning following acute and chronic ethanol exposure have been studied in a great number of experimental investigations. Results from many of these investigations can be difficult to interpret, particularly since a variety of techniques and exposure models are employed.
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Neurotoxicity with desmethylmisonidazole
The British Journal of Radiology, 1981There are now underway many clinical trials of misonidazole as an hypoxic cell sensitizer in radiotherapy. Because of the risk of neurotoxicity the total dose which may be given has been limited and in most trials a total of 12 g per square metre of surface area is set as the maximum.
Michael R.L. Stratford +2 more
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