Results 111 to 120 of about 191,466 (342)

Synthesis, Characterization, Biological Properties, and Sensor Applications of Novel Thiosemicarbazone Derivatives

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen   +4 more
wiley   +1 more source

Effects of oxytetracycline exposure in Oncorhynchus mykiss: oxidative defence system, peroxidative damage and neurotoxicity

open access: yesFrontiers in Marine Science, 2015
In recent years, the presence and effects of pharmaceutical drugs in aquatic ecosystems has received increasing attention from the scientific community.
Sara Rodrigues   +2 more
doaj   +1 more source

The ROCK inhibitor Fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic spine loss in rat hippocampus [PDF]

open access: yes, 2016
Indexación: Web of Science; Scopus.Background: Dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression.
Aguayo, F.   +12 more
core   +1 more source

Fusion Pores as Regulators of Quantal Size and Cellular Physiology

open access: yesBioEssays, EarlyView.
During regulated exocytosis, membrane fusion regulatory factors act directly on SNAREs and membrane lipids to control fusion pore dynamics. This, in turn, leads to a differential amount of cargo release (referred to in this article as “quantal size”) across various cell types, thereby triggering distinct physiological cues.
Bhavya R. Bhaskar   +3 more
wiley   +1 more source

Elucidating the pivotal molecular mechanisms, therapeutic and neuroprotective effects of lithium in traumatic brain injury

open access: yesBrain and Behavior
Introduction Traumatic brain injury (TBI) refers to damage to brain tissue by mechanical or blunt force via trauma. TBI is often associated with impaired cognitive abilities, like difficulties in memory, learning, attention, and other higher brain ...
Seidu A. Richard
doaj   +1 more source

Oméga 3 et neurotransmission cérébrale

open access: yesOléagineux, Corps gras, Lipides, 2004
Les acides gras polyinsaturés (AGPI) sont des constituants structuraux fondamentaux du système nerveux central (SNC) dont la teneur conditionne le fonctionnement des cellules neuronales. Ils sont des acteurs de la communication intercellulaire, notamment
Vancassel Sylvie
doaj   +1 more source

Insulin signaling controls neurotransmission via the 4eBP-dependent modification of the exocytotic machinery

open access: yeseLife, 2016
Altered insulin signaling has been linked to widespread nervous system dysfunction including cognitive dysfunction, neuropathy and susceptibility to neurodegenerative disease.
Rebekah Elizabeth Mahoney   +2 more
doaj   +1 more source

Recovery of hippocampal functions and modulation of muscarinic response by electroacupuncture in young diabetic rats [PDF]

open access: yes, 2017
The muscarinic receptor response to acetylcholine regulates the hippocampal-related learning, memory, neural plasticity and the production and processing of the pro-nerve growth factor (proNGF) by hippocampal cells.
Berretta, Erica   +9 more
core   +2 more sources

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