Results 131 to 140 of about 229,968 (342)

Brain serotonin synthesis capacity in obsessive-compulsive disorder: effects of cognitive behavioral therapy and sertraline. [PDF]

, 2018
Cognitive behavioral therapy (CBT) and selective serotonin reuptake inhibitors (SSRIs) are both effective treatments for some patients with obsessive-compulsive disorder (OCD), yet little is known about the neurochemical changes related to these ...
Barsoum, Amir, Benkelfat, Chawki, Berney, Alexandre, Cottraux, Jean, Diksic, Mirko, Gravel, Paul, Leyton, Marco, Lissemore, Jennifer I, Nordahl, Thomas E, Pinard, Gilbert, Sibon, Igor, Sookman, Debbie   +11 more
core   +2 more sources

Astrocytic GABA transporter activity modulates excitatory neurotransmission

Nature Communications, 2016
Astrocytes are ideally placed to detect and respond to network activity. They express ionotropic and metabotropic receptors, and can release gliotransmitters.
Kim Boddum, Thomas P. Jensen, Vincent Magloire, U. Kristiansen, D. Rusakov, I. Pavlov, M. Walker   +6 more
semanticscholar   +1 more source

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

Advanced Science, EarlyView.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien, Aneeth Kakkanattu Arunkumar, Rosalind Cross, Emilie Sunnucks, Frank Vollmer   +4 more
wiley   +1 more source

Effects of oxytetracycline exposure in Oncorhynchus mykiss: oxidative defence system, peroxidative damage and neurotoxicity

Frontiers in Marine Science, 2015
In recent years, the presence and effects of pharmaceutical drugs in aquatic ecosystems has received increasing attention from the scientific community.
Sara Rodrigues, Alberto Teodorico Correia, Bruno Silva Nunes   +2 more
doaj   +1 more source

Exosome: A novel neurotransmission modulator or non-canonical neurotransmitter?

Ageing Research Reviews, 2022
Xiaohuan Xia, Yi Wang, Ying Qin, Shu Zhao, Jialin C. Zheng   +4 more
semanticscholar   +1 more source

An optimized fluorescent probe for visualizing glutamate neurotransmission

Nature Methods, 2013
We describe an intensity-based glutamate-sensing fluorescent reporter (iGluSnFR) with signal-to-noise ratio and kinetics appropriate for in vivo imaging.
J. Marvin, B. Borghuis, L. Tian, Joseph Cichon, Mark T. Harnett, Jasper Akerboom, A. Gordus, S. Renninger, Tsai-Wen Chen, Cori Bargmann, M. Orger, E. Schreiter, J. Demb, W. Gan, S. Hires, L. Looger   +15 more
semanticscholar   +1 more source

Enzyme‐Inspired Hydrogen‐Bonded Organic Frameworks for Synergistic Capture, Detection, and Degradation of Nerve Agent Simulants

Advanced Science, EarlyView.
FDU‐HOF‐5, an enzyme‐inspired hydrogen‐bonded framework, enables targeted capture, real‐time visual alert, and detoxification of nerve agent simulants through biomimetic sites and multivalent interactions. Integrable into protective gear, it pioneers on‐site threat monitoring strategies for persistent neurotoxic hazards, advancing smart, responsive ...
Jiabao Liu, Guanglai Mo, Xiangyu Gao, Yingjia Deng, Yijin Wang, Qingyu Niu, Yujie Lei, Bin Fei, Joanne Yip, Zhaozhen Zhang, Jie Wu, Yunbo Bi, Kaikai Ma, Zhiqiang Li, Peng Li   +14 more
wiley   +1 more source

Insulin signaling controls neurotransmission via the 4eBP-dependent modification of the exocytotic machinery

eLife, 2016
Altered insulin signaling has been linked to widespread nervous system dysfunction including cognitive dysfunction, neuropathy and susceptibility to neurodegenerative disease.
Rebekah Elizabeth Mahoney, Jorge Azpurua, Benjamin A Eaton   +2 more
doaj   +1 more source

Neurochemical substrates and neuroanatomical generators of the event-related P300 [PDF]

, 1999
The present review focuses on the current knowledge of the neurochemical processes and neuronal structures involved in the generation of P300. The increasing knowledge in this area facilitates the physiological interpretation of P300 findings as well as ...
Bottlender, Ronald, Frodl-Bauch, Thomas, Hegerl, Ulrich   +2 more
core   +1 more source

Zebrafish Get Connected: Investigating Neurotransmission Targets and Alterations in Chemical Toxicity

Toxics, 2016
Neurotransmission is the basis of neuronal communication and is critical for normal brain development, behavior, learning, and memory. Exposure to drugs and chemicals can alter neurotransmission, often through unknown pathways and mechanisms.
Katharine A. Horzmann, J. Freeman
semanticscholar   +1 more source