Results 141 to 150 of about 191,466 (342)
Status epilepticus: Updates on mechanisms and treatments
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley +1 more source
ABSTRACT Objective To compare the efficacy and safety of lisdexamfetamine, topiramate, and naltrexone/bupropion for treating binge eating disorder (BED) using network meta‐analysis. Method We systematically searched PubMed, Scopus, ClinicalTrials.gov, and Cochrane Central up to February 2025 for randomized controlled trials evaluating these medications
Tamer Hodrob +5 more
wiley +1 more source
Non‐specific actions of the non‐peptide tachykinin receptor antagonists, CP‐96, 345, RP 67580 and SR 48968, on neurotransmission [PDF]
Zun‐Yi Wang +3 more
openalex +1 more source
Plasma MUFAs, n‐6 PUFAs (particularly LA), and n‐3 PUFAs (particularly non‐DHA n‐3 PUFAs) were found to be inversely associated with dementia risk. The interactions with APOE genotypes and genetic risk score were also observed, as well as the mediation of serum biomarkers. The study highlights the importance of refining plasma fatty acid profiles based
Hao Ye +11 more
wiley +1 more source
Inhibition of nitric oxide synthesis reveals non‐cholinergic excitatory neurotransmission in the canine proximal colon [PDF]
C. William Shuttleworth +2 more
openalex +1 more source
Neuronal THY1 Signaling Maintains Astrocytes in a Quiescent State
THY1‐bearing neurons keep astrocytes in a quiescent state via the interaction with ITGB1. Depletion of THY1 supports the development of a partially activated astrocyte phenotype. Neuronal THY1 is involved in the maintenance and restoration of tissue homeostasis in the brain. ABSTRACT THY1 is a cell surface protein of mature neurons.
Juliane Loui +6 more
wiley +1 more source
Age-related increase of kynurenic acid in human cerebrospinal fluid-IgG and beta(2)-microglobulin changes [PDF]
Kynurenic acid (KYNA) is an endogenous metabolite in the kynurenine pathway of tryptophan degradation and is an antagonist at the glycine site of the N-methyl-D-aspartate as well as at the alpha 7 nicotinic cholinergic receptors. In the brain tissue KYNA
Baran, H +5 more
core
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U +6 more
wiley +1 more source
Comparison of neurotransmission with nerve trunk and transmural field stimulation in guinea‐pig mesenteric artery. [PDF]
Kathleen D. Keef +4 more
openalex +1 more source

