Results 161 to 170 of about 224,377 (390)

The effect of profound cooling on adrenergic neurotransmission in canine cutaneous veins. [PDF]

, 1981
Nancy J. Rusch, J. T. Shepherd, Paul M. Vanhoutte   +2 more
openalex   +1 more source

Safety and Efficacy of the NMDA‐2b‐Selective Negative Allosteric Modulator BI 1569912: A Phase Ib Randomized Trial in Major Depressive Disorder

Clinical Pharmacology &Therapeutics, EarlyView.
Selective N‐methyl‐D‐aspartate receptor subunit 2b negative allosteric modulators (NR2B NAMs) are being explored as potential new treatment options for major depressive disorder (MDD). This Phase Ib, randomized, double‐blind, placebo‐controlled, parallel‐group trial was conducted in adults (N = 59) with moderate‐to‐severe MDD and insufficient response ...
Roger S. McIntyre, Gerard Sanacora, David P. Walling, Elan A. Cohen, Shishuka Malhotra, Holger Rosenbrock, Manuela Schmitz, Andreas Scholz, Sigurd D. Süssmuth, Franco De Crescenzo   +9 more
wiley   +1 more source

Neuroendocrine evaluation of catecholaminergic neurotransmission in mania [PDF]

, 1987
Marc Ansseau, R. von Frenckell, Jean-Luc Cerfontaine, Patrick Papart, Georges Franck, M Timsit-Berthier, Vincent Geenen, Jean‐Jacques Legros   +7 more
openalex   +1 more source

Biomimetic chloroplasts: Two‐phase microfluidic platforms with selective permeability for artificial photosynthesis

Droplet, EarlyView.
We present a biomimetic chloroplast system that integrates light‐dependent and light‐independent reactions, reaction compartments, and selectively permeable interfaces using a biphasic microfluidic droplet platform. This system enables continuous substrate–product exchange, mitigating product inhibition and side reactions, thus enhancing reaction ...
Guanxiong Wang, Meiying Hong, Chonghui Yang, Menghan Yang, Gaozhen Zhao, Haixia Liu, Rui Shen, Siping Wang, Xuming Zhang, Xiaowen Huang, Yaolei Wang   +10 more
wiley   +1 more source

Effects of anoxia and recovery on the neurotransmission and level of high-energy phosphates in thin hippocampal slices from the guinea-pig [PDF]

, 1989
Kazushi Yoneda, Yuko Okada
openalex   +1 more source

Seminar in Epileptology: Normal awake and sleep patterns, interictal abnormalities, and ictal patterns on scalp EEG

Epileptic Disorders, EarlyView.
Abstract The accurate interpretation of scalp EEG remains an instrumental diagnostic component of epilepsy care. Knowledge of what constitutes normal EEG findings, non‐epileptiform abnormalities, and epileptiform patterns—both ictal and interictal—is essential for appropriate patient management.
Juan Luis Alcala‐Zermeno, Roohi Katyal, Birgit Frauscher, Donald Schomer, Michael R. Sperling, Roy Strowd, William O. Tatum, Elaine Wirrell, Sándor Beniczky, Fábio A. Nascimento   +9 more
wiley   +1 more source

TUBA1A‐related tubulinopathy associated with the infantile epileptic spasms syndrome and atypical absence seizures

Epileptic Disorders, EarlyView.
Abstract Patients with TUBA1A pathogenic variants may present with complex brain malformation, intellectual disability, and epilepsy. The epilepsy phenotype is varied, ranging from mild to severe, with epileptic spasms and focal seizures being the most common seizure types.
Andy Cheuk‐Him Ng, Morris H. Scantlebury   +1 more
wiley   +1 more source

Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum

Neuron, 2020
M. Kuijpers, Gaga Kochlamazashvili, Alexander Stumpf, D. Puchkov, Aarti Swaminathan, Max T. Lucht, E. Krause, Tanja Maritzen, D. Schmitz, V. Haucke   +9 more
semanticscholar   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source