Results 241 to 250 of about 224,377 (390)

Ligand Recognition and Function of TAARs

open access: yesSensory Neuroscience, EarlyView.
The trace amine‐associated receptor (TAAR) family represents a highly conserved group of G protein‐coupled receptors (GPCRs) in vertebrates. TAARs specifically bind to different amine ligands and mediate a variety of physiological and behavioral processes.
Kang‐Ying Qian   +3 more
wiley   +1 more source

Bypassing Endocytic Barriers: Visualizing Membrane Fusion and Endosomal Escape of Cubic Phase Lipid Nanoparticles (Cubosomes)

open access: yesSmall, EarlyView.
This study uses advanced microscopy techniques, including transmission electron microscopy, scanning electron microscopy (SEM), cryogenic SEM, and live‐cell fluorescence imaging, to investigate lipid cubosome interactions with mammalian cells. It provides the first direct nanoscale evidence of cubosome membrane fusion with plasma and endosomal ...
Sue Lyn Yap   +5 more
wiley   +1 more source

Plasma Ammonia Levels Predict Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt Placement

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Placement of a transjugular intrahepatic portosystemic shunt (TIPS) is an effective treatment for portal hypertension. Overt hepatic encephalopathy (oHE) is a complication after TIPS associated with increased morbidity. Elevated ratio of plasma ammonia (AMM) levels compared to the local upper limit of normal (ULN) has been ...
Lisa Sandmann   +10 more
wiley   +1 more source

Nanotechnology and cell death: Revolutionizing disease treatment with nanoparticle strategies

open access: yesVIEW, EarlyView.
Traditional disease treatments often face issues such as poor drug targeting and significant side effects, with many complex diseases lacking effective therapies. Our research utilizes tiny nanomaterials to treat diseases by regulating natural cell death processes, improving the immune environment, etc., enabling drugs to act more precisely.
Yiwen Wan   +6 more
wiley   +1 more source

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