Results 251 to 260 of about 191,466 (342)

Intersection of epilepsy and cardiac health: Insights from electrocardiography and syndromic associations

Epilepsia, EarlyView.
Abstract Epilepsy is a chronic neurological condition marked by recurrent, uncontrolled seizures. Identifying comorbidities in epilepsy is critical for preventing mortality. Among these, the autonomic nervous system's role in epilepsy often manifests as cardiac disorders. Patients with epilepsy (PWE), particularly those with poorly controlled seizures,
Enes Akyuz, Feyza Sule Aslan, Tugba Eyigurbuz   +2 more
wiley   +1 more source

Bidirectional crosstalk between microglia and serotonin signaling in neuroinflammation and CNS disorders. [PDF]

Front Immunol
Zheng Y, Xu L.
europepmc   +1 more source

Alterations in sympathetic neurotransmission and vascular reactivity in fructose-induced hypertensive rats

, 2000
Yoshinobu Takata, Yuji Matsumoto, Hitoshi Kato   +2 more
openalex   +1 more source

Neuronal oscillatory imbalances in GNAO1‐related disorders associated with disease severity

Epilepsia, EarlyView.
Abstract Objective This study investigates excitatory/inhibitory (E/I) imbalances in GNAO1‐related disorders (GNAO1‐RD), linking neuronal dysfunction to clinical severity using E/I‐sensitive electroencephalography (EEG) analyses. Methods We conducted an observational study involving 12 children with GNAO1‐RD caused by pathogenic variants and 36 age ...
Tongyu Wang, Jana Domínguez‐Carral, William Grant Ludlam, Mar Junyent Segarra, Montserrat Fornaguera Marti, Hilgo Bruining, Kirill A. Martemyanov, Klaus Linkenkaer‐Hansen, Juan Dario Ortigoza‐Escobar   +8 more
wiley   +1 more source

Acetylcholinesterase as a Multifunctional Target in Amyloid-Driven Neurodegeneration: From Dual-Site Inhibitors to Anti-Agregation Strategies. [PDF]

Int J Mol Sci
Grabowska W, Bijak M, Szelenberger R, Gorniak L, Podogrocki M, Harmata P, Cichon N.   +6 more
europepmc   +1 more source

Role of nitric oxide in sympathetic neurotransmission in the rat kidney

, 2000
Hideki Tanioka, Kouichi Nakamura, Hiroaki Hisa, Susumu Satoh   +3 more
openalex   +1 more source

Cannabidiol attenuates epileptic phenotype and increases survival in a mouse model of developmental and epileptic encephalopathy type 1

Epilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathy type 1 (DEE1) is a rare drug‐resistant pediatric epilepsy caused by trinucleotide repeat expansions in the X‐linked ARX gene, leading to elongation of the first polyalanine tract. It presents with early onset tonic seizures or spasms, developmental and cognition delay, and high risk of ...
Lucia Verrillo, Fabio Arturo Iannotti, Denise Drongitis, Katiuscia Martinello, Loredana Poeta, Adriano Barra, Gaetano Terrone, Sergio Fucile, Vincenzo Di Marzo, Maria Giuseppina Miano   +9 more
wiley   +1 more source

Alterations in nitric oxide-dependent sympathetic neurotransmission of peripheral vascular beds of rats with chronic heart failure

, 2000
Yoshihisa Nasa, Chiharu Yoshikawa, Akiko Matsuoka, Toshiyuki Maki, Masaya Mori, Hiroyuki Yoshida, Satoshi Takeo   +6 more
openalex   +1 more source

Medial septum parvalbumin‐expressing inhibitory neurons are impaired in a mouse model of Dravet syndrome

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a severe neurodevelopmental disorder caused by pathogenic variants in the SCN1A gene, which encodes the voltage‐gated sodium channel Nav1.1 α subunit. Experiments in animal models of DS—including the haploinsufficient Scn1a+/− mouse—have identified impaired excitability of interneurons in the hippocampus and ...
Limei Zhu, Yiannos Demetriou, Joseph Barden, Juan Disla, Meiling Zhao, Joanna Mattis   +5 more
wiley   +1 more source

An endothelium-derived factor modulates purinergic neurotransmission in mesenteric arterial smooth muscle of hamster

, 2000
Sharada Thapaliva, Havato Matsuyama, Tadashi Takewaki   +2 more
openalex   +1 more source