Results 271 to 280 of about 191,466 (342)

Peripheral blood mononuclear cell secretome from patients with autoimmune encephalitis promotes seizures in vitro

Epilepsia, EarlyView.
Abstract Objective Autoimmune encephalitis (AE) is characterized by inflammatory processes in the central nervous system and frequently presents with seizures. Even though an ictogenic potential has been shown for some antibodies against neuronal surface antigens (NSAbs), AE pathophysiology is complex, and NSAbs‐independent mechanisms are likely to ...
Sara Prevosti, Alessio Passalacqua, Maria Cristina Regondi, Giada D'Ambrosio, Alessandra Morano, Michele Romoli, Giulia Maira, Flavio Villani, Pietro Mattioli, Diego Franciotta, Andrea Stabile, Marco de Curtis, Matteo Gastaldi, Francesco Deleo, Laura Librizzi   +14 more
wiley   +1 more source

Neuroactive Phytochemicals as Multi-Target Modulators of Mental Health and Cognitive Function: An Integrative Review. [PDF]

Int J Mol Sci
Tkaczenko H, Buyun L, Kołodziejska R, Kamiński P, Kurhaluk N.   +4 more
europepmc   +1 more source

Editorial for the Special Issue: Monoamine Transporters in Health and Disease [PDF]

, 2017
Daws, Lynette C., Gasser, Paul J.
core   +1 more source

Exploratory study of peripheral immune changes associated with diffusion MRI multi‐compartment model in temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Studies in temporal lobe epilepsy (TLE) have shown that focal inflammation is a key contributor to seizure initiation and maintenance. However, most in vivo studies to date have focused on positron emission tomography (PET) findings. In this exploratory study, we assessed the relationship between multicompartment Neurite Orientation ...
Jerzy P. Szaflarski, Rodolphe Nenert, Huixian Hong, Christina Mueller, Ayushe A. Sharma, Hongwei Qin, Etty N. Benveniste   +6 more
wiley   +1 more source

Electroacupuncture as adjunctive therapy for insomnia via targeting the GABAergic microbiota-gut-brain axis: a mini review. [PDF]

Front Psychiatry
Wang X, Yan L, Zhang X, Liu X, Yang B.
europepmc   +1 more source

Role of alpha-synuclein in the regulation of dopamine neurotransmission in the striatum [PDF]

Chadchankar, Heramb
core  

Neocortical neurogenesis: a proneural gene perspective

The FEBS Journal, EarlyView.
The neocortex is a mammalian‐specific brain region responsible for higher‐order cognitive functioning that shares fundamental similarities across species, but which is larger and more complex in humans. Proneural genes, encoding basic helix–loop–helix transcription factors (TFs), are evolutionarily conserved drivers of neurogenesis from fly to human ...
Lakshmy Vasan, Alexandra Moffat, Pierre Mattar, Carol Schuurmans   +3 more
wiley   +1 more source

The Role of GABA Pathway Components in Pathogenesis of Neurodevelopmental Disorders. [PDF]

Int J Mol Sci
Marilovtseva EV, Abdurazakov A, Kurishev AO, Mikhailova VA, Golimbet VE.   +4 more
europepmc   +1 more source

Posttranslational modifications of phosphodiesterase type 4 enzymes represent novel points for therapeutic targeting

The FEBS Journal, EarlyView.
Enzymes from the phosphodiesterase type 4 family (PDE4) coordinate physiological events driven by the cyclic AMP s(cAMP) signaling pathway by tightly controlling cAMP dynamics in many cell types. Key to this strict regulation is the myriad of posttranslational modifications that alter PDE4 activity, cellular location, and binding partner selection ...
Madihah Hussain, Gonzalo S. Tejeda, George S. Baillie   +2 more
wiley   +1 more source

The Central Nervous System Modulatory Activities of N-Acetylcysteine: A Synthesis of Two Decades of Evidence. [PDF]

Curr Issues Mol Biol
Cherneva DI, Kehayova G, Dimitrova S, Dragomanova S.   +3 more
europepmc   +1 more source