Results 281 to 290 of about 224,377 (390)

Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential

British Journal of Pharmacology, EarlyView.
Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley   +1 more source

Exogenous Administration of Delta-9-Tetrahydrocannabinol Affects Adult Hippocampal Neurotransmission in Female Wistar Rats. [PDF]

Int J Mol Sci
Neves AM, Leal S, Fonseca BM, Sá SI.
europepmc   +1 more source

Extended Synaptotagmin Localizes to Presynaptic ER and Promotes Neurotransmission and Synaptic Growth in Drosophila

Genetics, 2017
Koto Kikuma, Xiling Li, Daniel Kim, David Sutter, Dion K. Dickman   +4 more
semanticscholar   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Action potential-independent spontaneous microdomain Ca²⁺ transients-mediated continuous neurotransmission regulates hyperalgesia. [PDF]

Proc Natl Acad Sci U S A
Zhang Z, Yao J, Huo J, Wang R, Duan X, Chen Y, Xu H, Wang C, Chai Z, Huang R.   +9 more
europepmc   +1 more source

Autoimmunity in MASLD: Focus on autoantibodies, anti‐apolipoprotein A1 IgG and G protein‐coupled receptors

European Journal of Clinical Investigation, EarlyView.
This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano, Emmanuel Somm, François R. Jornayvaz, Nicolas Vuilleumier   +3 more
wiley   +1 more source

Condensate dynamics at the synapse: Phase separation tunes presynaptic function. [PDF]

PLoS Biol
Lützkendorf J, Sigrist SJ.
europepmc   +1 more source

Alterations in sympathetic neurotransmission and vascular reactivity in fructose-induced hypertensive rats

, 2000
Yoshinobu Takata, Yuji Matsumoto, Hitoshi Kato   +2 more
openalex   +1 more source

Intersection of epilepsy and cardiac health: Insights from electrocardiography and syndromic associations

Epilepsia, EarlyView.
Abstract Epilepsy is a chronic neurological condition marked by recurrent, uncontrolled seizures. Identifying comorbidities in epilepsy is critical for preventing mortality. Among these, the autonomic nervous system's role in epilepsy often manifests as cardiac disorders. Patients with epilepsy (PWE), particularly those with poorly controlled seizures,
Enes Akyuz, Feyza Sule Aslan, Tugba Eyigurbuz   +2 more
wiley   +1 more source

Role of nitric oxide in sympathetic neurotransmission in the rat kidney

, 2000
Hideki Tanioka, Kouichi Nakamura, Hiroaki Hisa, Susumu Satoh   +3 more
openalex   +1 more source