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Effects of Cannabinoids on Neurotransmission [PDF]
The CB1 cannabinoid receptor is widely distributed in the central and peripheral nervous system. Within the neuron, the CB1 receptor is often localised in axon terminals, and its activation leads to inhibition of transmitter release. The consequence is inhibition of neurotransmission via a presynaptic mechanism.
Szabo, Bela, Schlicker, Eberhard
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Dementia and neurotransmission
International Congress Series, 2002Abstract We investigated the influences of subcortical projections on the cerebral cortex in regard to glucose metabolism using positron emission tomography (PET) with F-18-labeled fluorodeoxyglucose (FDG). We speculate that not only cholinergic but also noradrenergic, serotonergic or dopaminergic projections onto the cerebral cortical neurons may be
H Fukuyama, H Saji
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2008
Publisher Summary This chapter presents a discussion on chemical neurotransmission and role of chemical neurotransmitters in the prefrontal cortex. It begins with an introduction to neurotransmitters and neurotransmitter receptors. Cells produce certain chemical substances called neurotransmitters and neuromodulators that, through specific receptors ...
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Publisher Summary This chapter presents a discussion on chemical neurotransmission and role of chemical neurotransmitters in the prefrontal cortex. It begins with an introduction to neurotransmitters and neurotransmitter receptors. Cells produce certain chemical substances called neurotransmitters and neuromodulators that, through specific receptors ...
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Neurotransmission in Hepatic Encephalopathy
1990After a careful characterization, a rat model of fulminant hepatic failure galactosamine-induced was utilized in order to evaluate the neurochemical changes and the histological alterations which occur during the developing of the encephalopathy. Following these studies, normal rats were treated with toxins claimed to be the primary agents of hepatic ...
M. Baraldi, M. L. Zeneroli
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Roles of glutamine in neurotransmission
Neuron Glia Biology, 2010Glutamine (Gln) is found abundantly in the central nervous system (CNS) where it participates in a variety of metabolic pathways. Its major role in the brain is that of a precursor of the neurotransmitter amino acids: the excitatory amino acids, glutamate (Glu) and aspartate (Asp), and the inhibitory amino acid, γ-amino butyric acid (GABA).
Michael Aschner +3 more
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Purinergic Neurotransmission and Neuromodulation
Annual Review of Pharmacology and Toxicology, 1983Conflicting views abound on the peripheral neurotransmitter and neuromodulator roles of purine compounds. Substantial organ- and species-related variations have become apparent. There is, however, a body of compelling evidence for such roles, if not so broad and ubiquitous as those envisioned (7) for the central nervous system.
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Neurotransmission und Neuromodulation
2012In diesem Kapitel werden die Besonderheiten des zentralen und peripheren Nervensystems bezuglich der Wirkmechanismen von Arzneimitteln besprochen. In diesem Sinne beschaftigt sich dieser Abschnitt mit der Synthese und Degradation, der prasynaptischen vesikularen Speicherung sowie der Freisetzung und Wiederverwertung von Transmittern.
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VIP and autonomic neurotransmission
Pharmacology & Therapeutics, 1989A variety of peptides have been proposed as transmitter candidates in non-cholinergic, non-adrenergic nerves. The nerves containing vasoactive intestinal polypeptide (VIP), which innervate blood vessels, non-vascular smooth muscle, mucosal epithelium and glands comprise a major and wide-spread population of the peptide-containing systems.
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Synapses and Neurotransmission
2016Our bodies are programmed for homeostasis. The neural network of the central and peripheral nervous system co-ordinate muscle movement, metabolic, cardio-respiratory and excretory functions. Both afferent signals from sensory receptors and efferent signals to muscles and glands are conveyed as action potentials skipping along myelinated or spreading ...
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