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The many ways astroglial connexins regulate neurotransmission and behavior
Glia, 2021Astrocytes have emerged as major players in the brain, contributing to many functions such as energy supply, neurotransmission, and behavior. They accomplish these functions in part via their capacity to form widespread intercellular networks and to ...
David Mazaud, Anna Capano, N. Rouach
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Neurotransmitters and Neurotransmission
2021Normal functioning of the human brain requires parallel and sequential innumerous neurotransmission processes that are fine-tuned by countless organic chemicals called neurotransmitters. Different neurotransmitters are expressed at a higher level in distinct areas of the brain signifying their physiological role.
Mageshwaran Lakshmanan, Elavarasi Pichai
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Annual Review of Nutrition, 2011
A subset of glutamatergic synapses in the central nervous system contains zinc; it is sequestered into the lumen of synaptic vesicles, where it colocalizes with glutamate. Extracellularly applied zinc is known to interact with various postsynaptic receptors and channels; however, the role of endogenous vesicular zinc is still an enigma.
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A subset of glutamatergic synapses in the central nervous system contains zinc; it is sequestered into the lumen of synaptic vesicles, where it colocalizes with glutamate. Extracellularly applied zinc is known to interact with various postsynaptic receptors and channels; however, the role of endogenous vesicular zinc is still an enigma.
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ACS Nano, 2020
Neurotransmission is the basis of brain functions, and controllable neurotransmission tuning constitutes an attractive approach for interventions in a wide range of neurologic disorders and for synapse-based therapeutic treatments.
Yiyuan Kang+9 more
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Neurotransmission is the basis of brain functions, and controllable neurotransmission tuning constitutes an attractive approach for interventions in a wide range of neurologic disorders and for synapse-based therapeutic treatments.
Yiyuan Kang+9 more
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Neurotransmission In The Auditory System
Otolaryngologic Clinics of North America, 1992Neurotransmitters and neuromodulators thought to be active on neurons in the cochlea, CN, and SOC have been reviewed. The variety of neurotransmitters and neuromodulators present and likely colocalized in these neurons are the chemical substrates that link morphologically and physiologically diverse neurons to process sound information.
Robert J. Wenthold+2 more
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Epilepsia, 1995
Summary: Some evidence indicates that in some types of focal epilepsy the enhanced excitability is due in part to impaired γ‐aminobutyric acid (GABA)ergic inhibitory feedback. One form that this can take is impaired excitatory input to GABAergic interneurons.
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Summary: Some evidence indicates that in some types of focal epilepsy the enhanced excitability is due in part to impaired γ‐aminobutyric acid (GABA)ergic inhibitory feedback. One form that this can take is impaired excitatory input to GABAergic interneurons.
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Neurotransmission: sites at which drugs modify neurotransmission
1983The idea that nerves may communicate with other cells by releasing small quantities of chemicals at their junctions may have arisen from observations of the effects of poisons on animals. It was found that some poisons could mimic the effects of stimulating certain nerves, and it must have occurred to somebody that nerves release chemicals in response ...
Zygmunt L. Kruk, Christopher J. Pycock
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Exercise and Brain Neurotransmission
Sports Medicine, 1995Physical exercise influences the central dopaminergic, noradrenergic and serotonergic systems. A number of studies have examined brain noradrenaline (norepinephrine), serotonin (5-hydroxytryptamine; 5-HT) and dopamine with exercise. Although there are great discrepancies in experimental protocols, the results indicate that there is evidence in favour ...
Romain Meeusen, K. De Meirleir
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2012
Publisher Summary This chapter discusses how ACh has been shown to regulate many physiologic functions within the central nervous system (CNS) modulating diverse functions including cognition, attention, and arousal. The availability of ACh for cholinergic transmission involves a highly coordinated process of ACh synthesis, vesicular packaging ...
Carrie K. Jones, Brett A. English
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Publisher Summary This chapter discusses how ACh has been shown to regulate many physiologic functions within the central nervous system (CNS) modulating diverse functions including cognition, attention, and arousal. The availability of ACh for cholinergic transmission involves a highly coordinated process of ACh synthesis, vesicular packaging ...
Carrie K. Jones, Brett A. English
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Astrocytes in glutamate neurotransmission
The FASEB Journal, 1995Astrocytes maintain ionic, amino acid neurotransmitter, and water homeostasis in the extracellular space of the brain. The anatomy of the cells, with their network formation and their capacity to react to and produce humoral and long-distance, slow-speed transfer of information within the syncytium, makes them appear to be a class of cells able to ...
Lars Rönnbäck, Elisabeth Hansson
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