Endocytic proteins drive vesicle growth via instability in high membrane tension environment [PDF]
Clathrin-mediated endocytosis (CME) is a key pathway for transporting cargo into cells via membrane vesicles. It plays an integral role in nutrient import, signal transduction, neurotransmission and cellular entry of pathogens and drug-carrying nanoparticles.
arxiv +1 more source
Glassy Carbon Microelectrode Arrays Enable Voltage-Peak Separated Simultaneous Detection of Dopamine and Serotonin Using Fast Scan Cyclic Voltammetry [PDF]
Progress in real-time, simultaneous in vivo detection of multiple neurotransmitters will help accelerate advances in neuroscience research. The need for development of probes capable of stable electrochemical detection of rapid neurotransmitter fluctuations with high sensitivity and selectivity and sub-second temporal resolution has, therefore, become ...
arxiv +1 more source
Statistical crossover and nonextensive behavior of the neuronal short-term depression [PDF]
The theoretical basis of neuronal coding, associated with short term degradation in synaptic transmission, is a matter of debate in the literature. In fact, electrophysiological signals are commonly characterized as inversely proportional to stimulus intensity.
arxiv +1 more source
Adenovirus mediated gene transfer in organotypic brain slices
A replication-defective adenovirus vector carrying the reporter gene encoding β-galactosidase was used to transfect organotypic slices maintained in culture for up to 1 month.
V. Ridoux+4 more
doaj
Introduction Traumatic brain injury (TBI) refers to damage to brain tissue by mechanical or blunt force via trauma. TBI is often associated with impaired cognitive abilities, like difficulties in memory, learning, attention, and other higher brain ...
Seidu A. Richard
doaj +1 more source
A Fluorescent Ratiometric Potassium Sensor Based on IPG4-Silica Microparticles for Selective Detection and Fluorescence Imaging of Potassium Cations [PDF]
Potassium cations play many important roles in living organisms, especially in electro-physiology, since they are involved in neurotransmission and muscle contractions. We report the synthesis of a ratiometric fluorescent microsensor for potassium (K+) detection, based on the fluorescent probe ION potassium green 4.
arxiv +1 more source
Quantifying constraints determining independent activation on NMDA receptors mediated currents from evoked and spontaneous synaptic transmission at an individual synapse [PDF]
A synapse acts on neural transmission through a chemical process called synapses fusion between pre-synaptic and post-synaptic terminals. Presynaptic terminals release neurotransmitters either in response to action potential or spontaneously independent of presynaptic activity.
arxiv
Enhanced average for event-related potential analysis using dynamic time warping [PDF]
Electroencephalography (EEG) provides a way to understand, and evaluate neurotransmission. In this context, time-locked EEG activity or event-related potentials (ERPs) are often used to capture neural activity related to specific mental processes. Normally, they are considered on the basis of averages across a number of trials.
arxiv +1 more source
Stochastic Adaptive Activation Function [PDF]
The simulation of human neurons and neurotransmission mechanisms has been realized in deep neural networks based on the theoretical implementations of activation functions. However, recent studies have reported that the threshold potential of neurons exhibits different values according to the locations and types of individual neurons, and that the ...
arxiv
Hibernation is an amazing animal strategy to survive when the environmental temperature is very low and food resources are scarce. Successful hibernation requires a variety of complex biological adaptations, in which the brain plays a central regulatory ...
E. Roda+4 more
doaj +1 more source