Alteration of colonic excitatory tachykininergic motility and enteric inflammation following dopaminergic nigrostriatal neurodegeneration [PDF]
Background: Parkinson's disease (PD) is frequently associated with gastrointestinal (GI) symptoms, including constipation and defecatory dysfunctions. The mechanisms underlying such disorders are still largely unknown, although the occurrence of a bowel ...
Antonioli, Luca+13 more
core +3 more sources
Using the maternal immune stimulation model of schizophrenia to investigate the therapeutic efficacy of neuromodulation techniques [PDF]
The present work used a neurodevelopmental rodent model of schizophrenia, namely the maternal immune stimulation (MIS) model, to study the potency of electrical neuromodulation techniques to ameliorate and even prevent schizophrenia-relevant behavioral ...
Hadar, Ravit
core +1 more source
Glycine receptor autoantibodies disrupt inhibitory neurotransmission
Immunoglobulin G autoantibodies to glycine receptors are found in many patients with progressive encephalomyelitis with rigidity and myoclonus (PERM). Crisp et al.
S. Crisp+11 more
semanticscholar +1 more source
Additive Manufacturing of Neuromorphic Systems
The crossover of additive Manufacturing (AM) and neuromorphic engineering promises a new paradigm in the fabrication of intelligent hardware—one that is sustainable, scalable, cost‐efficient, and customizable. The AM‐printed neuromorphic hardware (electronics and mechanical systems) is examined, and we discussed the technological integration.
Jiongyi Yan+3 more
wiley +1 more source
Corticosterone Acts in the Nucleus Accumbens to Enhance Dopamine Signaling and Potentiate Reinstatement of Cocaine Seeking [PDF]
Stressful life events are important contributors to relapse in recovering cocaine addicts, but the mechanisms by which they influence motivational systems are poorly understood.
Baker, David A.+10 more
core +2 more sources
Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain
A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng+11 more
wiley +1 more source
Beneficial effects of omega-3 fatty acid supplementation in schizophrenia: possible mechanisms
Background Schizophrenia is a serious long-term psychotic disorder marked by positive and negative symptoms, severe behavioral problems and cognitive function deficits.
Mei-Chi Hsu+2 more
doaj +1 more source
Glutamatergic Neurotransmission in Alcoholism
Substance abuse and dependence is the most common psychiatric problem. Alcohol is the most commonly abused substance and most people who abuse other substance(s) abuse alcohol at the same time ...
openaire +3 more sources
Fluorescent Biosensors for Neurotransmission and Neuromodulation: Engineering and Applications
Understanding how neuronal activity patterns in the brain correlate with complex behavior is one of the primary goals of modern neuroscience. Chemical transmission is the major way of communication between neurons, however, traditional methods of ...
A. Leopold+2 more
semanticscholar +1 more source
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar+7 more
wiley +1 more source